Diabetes mellitus is a term for a group of disorders that cause elevated blood sugar (glucose) levels in the body. Glucose is a critical source of energy for your brain, muscles, and tissues.
When you eat, your body breaks down carbohydrates into glucose. This triggers the pancreas to release a hormone called insulin. Insulin acts as a “key” that allows glucose to enter the cells from the blood. If your body doesn’t produce enough insulin to effectively manage glucose, it can’t function or perform properly. This produces the symptoms of diabetes.
Uncontrolled diabetes can lead to serious complications by damaging blood vessels and organs. It can increase the risk of:
Nutrition and exercise can help manage diabetes, but it’s also important to track blood glucose levels. Treatment may include taking insulin or other medications.
Types of diabetes
Here’s a breakdown of the different types of diabetes:
- Prediabetes. Blood glucose levels are higher than what’s considered normal, but not high enough to qualify as diabetes.
- Type 1 diabetes. The pancreas produces no insulin.
- Type 2 diabetes. The pancreas doesn’t make enough insulin or your body can’t use it effectively.
- Gestational diabetes. Expectant mothers are unable to make and use all of the insulin they need during pregnancy.
According to the American Diabetes Association (ADA), people who develop type 2 diabetes nearly always have prediabetes. This means blood glucose levels are elevated, but not yet high enough to be considered diabetes. The Centers for Disease Control and Prevention (CDC) estimates 84 million adult Americans have prediabetes, and 90 percent go undiagnosed.
Type 1 diabetes
With type 1 diabetes, the pancreas can’t produce insulin. According to the ADA, 1.25 million Americans have this disorder. This is about 5 percent of all diagnosed cases. The ADA estimates that 40,000 people receive a type 1 diagnosis each year in the United States.
Type 2 diabetes
Type 2 diabetes is the most common form of diabetes. With this disorder, the pancreas can initially produce insulin, but your body’s cells can’t respond to it effectively. This is known as insulin resistance. The CDC notes that 90 to 95 percent of diagnosed cases are type 2 diabetes.
This form of diabetes develops during pregnancy. The CDC estimates between 2 and 10 percent of pregnancies in the United States are affected by gestational diabetes every year. According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), women with gestational diabetes will have a greater chance of developing type 2 diabetes within 10 years.
Prevalence and incidence
According to the CDC, more than 100 million adults in the United States are living with diabetes or prediabetes. They note that in 2015, 30.3 million Americans, or close to 10 percent of the population, had diabetes. Of that amount, the ADA estimates 7.2 million didn’t know they had it.
The CDC’s annual report shows that diabetes diagnoses for Americans age 18 and older are increasing, with new diagnoses occurring at about 1.5 million per year. Those numbers were equal for men and women.
Causes and risk factors
Previously known as juvenile diabetes, type 1 diabetes is usually diagnosed in childhood. Only about 5 percent of people with diabetes have type 1, estimates the ADA.
While factors such as genetics and certain viruses may contribute to this disease, its exact cause is unknown. There’s no current cure or any known prevention, but there are treatments to help manage symptoms.
The risk of developing type 2 diabetes increases as you get older. You’re also more likely to develop it if you’ve had gestational diabetes or prediabetes. Other risk factors include being overweight or having a family history of diabetes.
While you can’t completely eliminate the risk of type 2 diabetes, a healthy diet, weight control, and regular exercise may help prevent it.
Certain ethnicities are at higher risk of developing type 2 diabetes, too. These include:
- Native Americans
- Hawaiian/Pacific Islands Americans
Blindness is a common diabetes complication. Diabetic retinopathy, in particular, is the most common cause of blindness among people with diabetes. It’s a leading cause of vision loss among working-age adults, according to the National Eye Institute.
Diabetes is also a leading cause of kidney failure. Nervous system damage, or neuropathy, affects a large portion of people with diabetes.
Many people with diabetes have impaired sensation in the hands and feet, or carpal tunnel syndrome. Diabetes can also cause digestive problems and erectile dysfunction. The conditions also increases the risk of high blood pressure, heart disease, and stroke. Diabetes can also lead to amputation of the lower limb.
According to the ADA, diabetes is the seventh-leading cause of death in the United States.