Diabetes insipidus causes persistent thirst and frequent urination due to not having enough of the hormone vasopressin. Pituitary tumors and pituitary surgery are two potential causes.
Diabetes insipidus is a rare condition estimated to affect
According to the
Read on to learn more about the connection between pituitary tumors and diabetes insipidus.
Diabetes insipidus is usually caused when not enough of the hormone called vasopressin is released or your kidney doesn’t properly respond to this hormone.
Vasopressin is produced by a part of your brain called the hypothalamus and secreted through a gland at the base of your brain called the posterior pituitary gland.
Tumors on your pituitary gland or surrounding parts of your brain can push on the tissue in your posterior pituitary gland and cause vasopressin to not be secreted normally. When this happens, your kidneys don’t receive the signal that they should retain more water. Insufficient levels of vasopressin lead to persistent thirst and frequent urination.
The most common type of pituitary tumor is called adenoma. Adenomas develop in the anterior part of your pituitary gland and rarely cause diabetes insipidus. They usually only compress your posterior pituitary gland when they grow
The development of diabetes insipidus is more common among people with a rarer type of tumor called
Diabetes insipidus has also been reported as a complication of cancers that have spread to your pituitary gland from other locations. About
Diabetes insipidus is a condition characterized by not enough vasopressin being secreted and an imbalance in your body’s water supply.
It doesn’t cause pituitary tumors, but pituitary tumors and surgery to remove pituitary tumors can cause diabetes insipidus.
The part of your brain around your pituitary gland and hypothalamus is extremely delicate. Surgery can damage tissue in these sensitive parts of your brain and lead to temporary or permanent diabetes insipidus.
The chances of developing diabetes insipidus vary widely depending on the type of tumor you have and the surgical technique used to remove it. Symptoms usually start within a
Temporary diabetes insipidus has been reported in anywhere from
Permanent diabetes insipidus has been reported in
Transnasal means the surgery is performed through a hole in the bone at the back of your nasal cavities. Endoscopic and microsurgical approaches are minimally invasive techniques.
Diabetes insipidus has also been reported in up to
Other complications of pituitary surgery
Other complications of pituitary surgery include:
The most common symptoms of diabetes insipidus are:
If the condition is left untreated, it can cause severe dehydration that can lead to coma or death.
Pituitary tumors can also cause other symptoms. According to the American Association of Neurological Surgeons, protentional symptoms of craniopharyngioma include:
Diabetes insipidus can be treated with a synthetic version of antidiuretic hormone called
- as a nasal spray
- through injections
Most pituitary tumors are slow growing and noncancerous. Your life expectancy depends on your size and type of tumor.
People with pituitary adenomas have an excellent outlook if excess hormones aren’t being produced and they’re treated promptly.
Diabetes insipidus is a condition that causes persistent thirst and frequent urination. It can develop when pituitary tumors press on your posterior pituitary gland and impair the gland’s ability to secrete the hormone vasopressin.
Diabetes insipidus is also a common complication of pituitary surgery that can be permanent or temporary. It can be treated with a synthetic version of vasopressin called desmopressin.