CBD productsShare on Pinterest

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.

Cannabidiol (CBD) is one of the active compounds derived from the cannabis plant. But unlike tetrahydrocannabinol (THC), CBD doesn’t have the telltale intoxicating effects, which means it doesn’t produce a “high.” Instead, its use is therapeutic.

CBD is increasingly being explored as a treatment for myriad conditions, from high blood pressure to heart disease to endometriosis.

Endometriosis is a common gynecological condition in which tissue grows outside of the uterine cavity. This can cause pain, heavy bleeding, and fertility issues.

While clinical studies on CBD and endometriosis are limited, some people say it helps with symptoms.

Read on for a look at the research on CBD for managing endometriosis, as well as a few products you may want to try.

First, it’s important to clarify that CBD isn’t a cure for endometriosis. Still, it could help manage some symptoms associated with the condition, including pain and cramping.

While there isn’t any current research on CBD and endometriosis pain specifically, there are clinical trials in the works. In the meantime, some people claim that CBD helps them manage pain, in general. In a 2018 survey of 2,409 people, pain was the most commonly reported reason for using CBD.

Limited research backs CBD’s ability to reduce pain. Research from 2018 found that CBD works well for relieving chronic pain related to cancer, neuropathy, and fibromyalgia.

However, research from 2020 cautions that CBD doesn’t always relieve pain. In addition, a small 2021 study that compared CBD with a placebo for managing arthritis pain found no difference between the two.

Another small 2021 study tested the effects of CBD on pain in 15 healthy adults and found that pain outcomes can be affected by both using CBD and the expectations of receiving CBD.

Your body has what’s known as the endocannabinoid system (ECS). It’s made up of:

  • Endocannabinoids: These molecules are made by the human body. They’re similar to the cannabinoids found in cannabis. These compounds work on receptors found throughout the body.
  • Receptors: CB1 receptors are primarily found in the central nervous system. CB2 receptors are typically found in the peripheral nervous system.
  • Enzymes. Enzymes break down endocannabinoids after they’ve carried out their functions.

Some cannabinoids, like THC, are known to bind to ECS receptors. Other cannabinoids, like CBD, interact with the system in a different way. One theory is that CBD slows the process of breaking endocannabinoids down, allowing them to remain effective for longer.

Though the ECS was identified more than 20 years ago, researchers are still trying to fully understand its role in the body. So far, we know that it helps regulate processes in the body, including:

  • sleep
  • mood
  • appetite
  • memory
  • fertility and reproduction
  • pain sensations

Most significantly for people with endometriosis, research from 2017 suggests that the ECS interacts with many of the pain-associated mechanisms of this condition. Researchers say that influencing the ECS might be a good strategy for relieving pain.

CBD is available in many forms, including:

If you’re hoping to relieve symptoms of endometriosis, like pelvic pain and cramping, topicals applied directly to the abdomen or an oil taken beneath the tongue will likely be the most effective.

We chose these products based on criteria we believe indicate safety, quality, and transparency. Each product:

  • has completed third-party testing by an ISO 17025-compliant lab
  • is made with hemp grown in the United States
  • contains no more than 0.3 percent THC, according to the certificate of analysis (COA)
  • passes tests for pesticides, heavy metals, and molds, according to the COA

We also considered:

  • company certifications and manufacturing processes
  • product potency
  • overall ingredients
  • indicators of user trust and brand reputation, including:

Pricing guide

  • $ = under $30
  • $$ = $30–$60
  • $$$ = over $60

Best full-spectrum CBD oil for endometriosis

Lazarus Naturals Full Spectrum CBD Tincture

  • Price: $
  • CBD type: full spectrum
  • CBD potency: 750 mg per 1-milliliter (mL) bottle
  • COA: available on product page

This full-spectrum, high-potency CBD oil is available in four flavors and four sizes. Customers praise it for its flavors and efficacy.

The oil is certified organic and cruelty-free. Lazarus Naturals also has an assistance program for veterans, people on long-term disability, and low-income households.

Best CBD cream for endometriosis

Medterra Relief + Recovery Cream

  • Price: $$
  • CBD type: isolate
  • CBD potency: 250 mg per 1.7-ounce (oz.) container
  • COA: available on product page

This cream is designed for relief from pain. Formulated with menthol and arnica, it provides a cooling effect.

Customers praise Medterra’s immediate pain relief and quick absorption. They also note it’s free of unpleasant odors and that a little goes a long way.

Best CBD patch for endometriosis

PureKana Infused CBD Patch

  • Price: $
  • CBD type: full-spectrum
  • CBD potency: 60 milligrams (mg) per patch
  • COA: available on product page

These patches are applied on or near the site of discomfort. They’re a good alternative to messy topicals or sublingual products.

According to PureKana, a single patch can be kept on for up to 4 days. The patch is waterproof, so it should stay put.

With aloe vera and moisturizing coconut oil, the patches are also designed to be gentle on the skin and hypoallergenic. One thing to note is they do contain palm oil.

Best broad-spectrum CBD oil for endometriosis

Saha Self-Care Broad Spectrum CBD Tincture

  • Price: $$$
  • CBD type: broad spectrum
  • CBD potency: 1,000 mg per 1-oz. bottle
  • COA: available on product page

With a mild spearmint flavor, Saha Self-Care’s broad-spectrum oil is a good choice for anyone who wants to avoid THC.

According to Saha Self-Care, this CBD oil is a best seller, and customers love the cooling spearmint flavor. However, there are no public customer reviews.

An important first step is to review the manufacturer’s instructions for use and dosing. However, it can be helpful to keep these guidelines in mind:

  • CBD oils are dropped beneath the tongue. They can also be added to foods and drinks.
  • CBD patches are applied directly to the skin.
  • CBD creams can be applied to the abdomen.

The golden rule of CBD use is to start low and go slow. Appropriate dosing is heavily dependent on your own body weight, body chemistry, product potency, and the condition you’re trying to relieve.

Expect a bit of trial and error as you explore CBD for symptoms of endometriosis, using the manufacturer’s recommendations and our CBD dosing guide as a starting point.

It’s not difficult to find CBD products online or in stores these days. But keep in mind that the FDA doesn’t regulate these products, beyond sending warning letters to brands that break the rules. That means you need to shop wisely.

Before using any CBD products, make a point of checking the brand thoroughly.

  • Look for a current and comprehensive COA. You should review the COA to make sure the product contains as much CBD and THC as you’re expecting it to. You can also take a look at contaminant testing results to make sure the product hasn’t been contaminated in the manufacturing process.
  • Consider whether the company is transparent. Review the brand’s website to see whether they’re forthcoming about the source of their hemp and their manufacturing processes.
  • Do a reputation check. Look online to confirm that the brand hasn’t received a letter of warning from the FDA or been involved in any lawsuits.
  • Check customer reviews. Reviews will give you a good idea of what past customers think of a brand’s products.

If you have any questions about a brand’s legitimacy, keep looking.

Also, keep in mind that any CBD products you find on Amazon likely aren’t the real deal. Amazon currently prohibits the sale of these products. Products advertised as CBD are probably hempseed products instead.

CBD has a good safety profile, according to the World Health Organization, but that doesn’t mean there can’t be side effects. Some people could experience:

  • changes in weight or appetite
  • diarrhea
  • fatigue

If you’re currently taking medications to manage symptoms of endometriosis or any other condition, speak with a doctor before trying CBD. CBD may interact with some medications.

CBD isn’t your only option for treating symptoms of endometriosis. There are also medical and surgical options designed to reduce symptoms and address complications.

These include:

If you’re experiencing pelvic pain or painful periods, speak with a doctor. That’s an important first step before trying to self-treat your symptoms at home with CBD or anything else.

If you’re currently using CBD for symptoms of endometriosis, but your symptoms aren’t improving, or if you notice any side effects, talk with a doctor right away.

. But it may help alleviate pain for some people. If you’re considering trying CBD for endometriosis, talk with a doctor first.

Is CBD Legal? Hemp-derived CBD products (with less than 0.3 percent THC) are legal on the federal level, but are still illegal under some state laws. Marijuana-derived CBD products are illegal on the federal level, but are legal under some state laws. Check your state’s laws and those of anywhere you travel. Keep in mind that nonprescription CBD products are not FDA-approved, and may be inaccurately labeled.


Jessica Timmons has been working as a freelance writer since 2007, covering everything from pregnancy and parenting to cannabis, chiropractic, stand-up paddling, fitness, martial arts, home decor, and much more. Her work has appeared in mindbodygreen, Pregnancy & Newborn, Modern Parents Messy Kids, and Coffee + Crumbs. See what she’s up to now at jessicatimmons.com.