Many people with testicular cancer don’t have a family history of it. Still, your risk may be much higher if you have a parent or sibling with the disease. But environment and hormones also play a role.
All cancer is genetic. That’s because cancer stems from genetic changes to your DNA, called mutations. These mutations cause cells to grow and divide out of control. Sometimes, people can pass down those genetic mutations from one generation to the next.
If a parent carries a gene that may increase the risk of testicular cancer, it’s possible they could pass it down to you. In fact, this is
Even so, many people who develop testicular cancer don’t have a family history. This means that other factors can affect your risk.
Keep reading to discover how your genetics can influence your risk of testicular cancer, what other factors play a role, and what you can do to lower your risk.
Testicular cancer results from DNA changes in testicular cells. But these changes occur due to many influences, including:
- random mutations
- inherited mutations
- carcinogens, like pesticides, radiation, or cigarette smoke
- infections, like HIV
- hormonal influences
Inherited mutations are part of your DNA from the start of your existence. But other mutations can occur at any time during your life, including when you’re still a fetus.
This is largely due to genetics, but it may also be due to similar environmental factors. A
The above study came to its conclusions by examining sets of twins. Twin studies allow us to assess the influence of genetic and environmental factors.
This is because sets of twins have identical genes and a shared environment through pregnancy. They also tend to have similar lifestyle and environmental exposures through childhood and often beyond.
How likely am I to have testicular cancer if my parent had it?
According to a
But that doesn’t mean you’ll develop testicular cancer. Many other factors can affect your risk.
As of 2021, scientists have identified
Some of the genes
While family history may significantly increase your risk of testicular cancer, other risk factors play a role. These include:
Having an undescended testicle (cryptorchidism) may increase your risk of testicular by
If testicular cancer does develop, it’s
This suggests that an undescended testicle doesn’t cause you to have testicular cancer. Instead, another health condition could increase your risk of testicular cancer and cryptorchidism.
Previous testicular cancer
Even after effectively treating testicular cancer in one testicle, about
Indications of testicular cancer
Early symptoms of testicular cancer
- a lump on your testicle
- testicular swelling and pain
- breast growth
- early puberty
There’s no known way to prevent testicular cancer. Most of the risk factors are out of your control. But if you have a family history, you can take steps to lower your risk or improve your outlook if you do develop cancer.
Testicular cancer is uncommon. But it may be more likely to run in families than other, more common, cancers. Having a first-degree relative with
Still, many people with testicular cancer don’t have a family history of it. You may be more likely to develop testicular cancer due to other factors. Carcinogens, infections, and having an undescended testicle can all contribute to your testicular cancer risk. A random genetic mutation can also be the cause.
If you have a parent or sibling with testicular cancer, you may want to consider genetic testing. Although it’s not definitive, it could let you know if you have a genetic mutation that may increase your risk.
But the outlook for people with testicular cancer is generally good. According to the American Cancer Society, the 5-year relative survival rate is