Chances are you’ve either contracted the human papillomavirus or know someone who has. At least 100 different types of human papillomavirus (HPV) exist.
HPV is the most common sexually transmitted infection (STI) in the United States. Certain types of HPV can cause cervical cancer. But can HPV cause other types of cancer, like breast cancer?
Breast cancer occurs when cancer forms in the cells of the breasts. According to 2015 statistics from the CDC, breast cancer had the highest rate of new cases among women in the United States compared to other cancers that year. It also had the second highest death rate of any type of cancer in U.S. women.
While more common in women, this type of cancer can occur in men as well.
Breast cancer usually starts in the milk-producing glands, called lobules, or the ducts that drain milk to the nipple.
Noninvasive cancers, also known as carcinoma in situ, stay within the lobules or ducts. They don’t invade normal tissue around or beyond the breast. Invasive cancers grow out into and beyond surrounding healthy tissue. Most breast cancers are invasive.
Breastcancer.org states that 1 in 8 women in the United States will develop invasive breast cancer in their lifetime. This organization also reports that in 2018, approximately 266,120 new diagnoses of invasive and 63,960 diagnoses of noninvasive breast cancer are estimated to occur in U.S. women.
Although researchers have connected HPV to cervical cancer, suggesting a link exists between breast cancer and HPV is controversial.
In one 2009 study, researchers used 28 breast cancer specimens and 28 noncancerous breast cancer specimens to see if high-risk HPV was in the cells. Results showed high-risk HPV gene sequences in two of the cell lines.
In a 2017 study, both cancerous and benign breast tissue samples were analyzed. Researchers were able to detect high-risk HPV DNA sequences and proteins in some malignant breast cancer tissue samples.
However, they also found evidence of high-risk HPV in some of the benign samples as well. They theorize that there may be a possibility that breast cancer may eventually develop in these people, but note that further investigation and follow-ups are required to either confirm or disprove this.
Taken together with the 2009 study, this underlines the importance of continuing to investigate a possible link between breast cancer and HPV. More research is necessary.
No one knows exactly why breast cancer occurs. The environment, hormones, or a person’s lifestyle could all play a role in the development of breast cancer. It may also have genetic causes.
High-risk HPV can cause cancer if your immune system doesn’t eliminate the cells it infects. These infected cells can then develop mutations, which can cause cancer. Because of this, it’s possible that HPV could cause breast cancer, but not enough research exists to support that theory.
HPV isn’t currently considered a risk factor for breast cancer. Women are more likely to develop breast cancer than men. Other risk factors include:
- increasing age
- radiation exposure
- having a child at an older age
- not giving birth to any children
- starting your period at a young age
- beginning menopause later in life
- drinking alcohol
- a family history of breast cancer
Breast cancer isn’t often inherited, but genetic factors may play a role for some people. Eighty-five percent of the cases occur in women who have no family history of breast cancer.
The greatest risk factor for HPV is being sexually active.
Breast cancer prevention
You can’t prevent breast cancer. Instead, you should perform self-exams and get screening exams.
Recommendations about when you should start getting a mammogram or how frequently you get it vary.
The U.S. Preventive Services Task Force recommends that women begin getting mammograms when they’re 50 years old.
The American Cancer Society recommends that women start getting mammograms when they’re 45.
Both organizations say that starting screening at 40 years old may be appropriate for certain women. Talk to your doctor about when to begin screening and how frequently you should get mammograms.
Catching breast cancer early can help stop it from spreading and increase your chances of recovery.
You can help prevent HPV by doing the following:
Use latex condoms
You should use latex condoms every time you have sex. However, be aware that HPV is different from a typical STI in that you can contract it through areas that a condom doesn’t cover. Use as much caution as possible when engaging in sexual activity.
This is the best way to prevent cancer that’s due to HPV. The U.S. Food and Drug Administration (FDA) has approved three vaccines to prevent HPV:
- human papillomavirus bivalent vaccine (Cervarix)
- human papillomavirus quadrivalent vaccine (Gardasil)
- human papillomavirus 9-valent vaccine (Gardasil 9)
People between the ages of 9 and 14 years receive two shots over a six-month period. Anyone getting the vaccine later (between the ages of 15 and 26 years) receives three shots. You need to get all shots in the series for the vaccine to be effective.
These vaccines are approved for females and males ages 11 to 26. Gardasil 9 is now also approved for both men and women ages 27 to 45 who weren’t previously vaccinated.
You should also follow these tips:
- Know your sexual partners.
- Ask your partners questions about their sexual activity and how often they get tested.
- See your doctor to get screened for cancer if you’re a woman.
Current evidence doesn’t support a link between HPV and breast cancer. However, you can do the following:
- Talk to your doctor about an HPV vaccine.
- Always practice safe sex.
- Talk to your sexual partners about their sexual history.
- Follow your doctor’s recommendations for breast cancer screening.
- If you’re concerned that you may have an increased risk of breast cancer, discuss your risk factors with your doctor.
Preventing cancer isn’t always possible. However, you can increase your chances of catching and treating cancer early if you’re proactive.