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A colonoscopy is about as exciting as a trip to the dentist or DMV — OK, maybe even less exciting.

But for those at average risk of colon cancer, there’s an easier, less invasive way to screen for the disease from home. Fecal immunochemical tests (FITs) are a good option for those:

  • without lower gastrointestinal (GI) symptoms, as can come from hemorrhoids
  • without a history of colon cancer or an inflammatory bowel disease (IBD)
  • without siblings or parents who have been diagnosed with colon cancer before age 60
  • with no more than two relatives diagnosed at any age

Keep reading to learn more about these tests and see our picks for the best FIT options.

What is a FIT?

FIT is one type of colon cancer screening test that uses a stool (feces) sample. FIT screening checks for blood (hemoglobin) in your stool.

Blood in your stool, which may not be visible, can come from unusual growths in the colon or from other causes such as hemorrhoids.

FIT samples are often self-taken at home, even when the test is ordered by a doctor. This makes kits a good idea for sample collection. FITs can be convenient, less invasive, and more cost effective for people. They can be useful screening tools for preventive healthcare.

According to the American Cancer Society, FIT screening must be done yearly to appropriately check colon health.

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We looked for tests that:

  • you can easily take at home
  • are approved by the Food and Drug Administration (FDA)
  • are made by companies that use College of American Pathologists (CAP) accredited and Clinical Laboratory Improvement Amendments (CLIA) certified laboratories
  • are made by companies that offer good customer service and support

Our Brand and Content Integrity team also vetted all the options on our list, ensuring that each test met our medical and business standards.

FIT testPriceFDA approvalResults turnaroundPhysician consultationAccepts insurance or HSA/FSAFeatures
Everlywell FIT Colon Cancer Screening Test$49no5 days contacted only with positive test resultHSA/FSA onlymembership offers access to other tests monthly
LetsGetChecked at Home Colon Cancer Screening Test$89yes2–5 daysnursing team availableHSA/FSA onlykit arrives unmarked for privacy
Labcorp OnDemand Colorectal Cancer At-Home Test$89nonot listedcontacted by PWNHealth for certain test resultsHSA/FSA onlywell established network of labs
Pinnacle Biolabs Second Generation FIT$24.99FDA cleared for OTC use4–7 minutes noneitherfully done at home, results in minutes
Cologuard$649 maxyes2 weeks 5–20 minute session with a PWNHealth provider available•accepts insurance
may accept HSA/FSA
also tests DNA, detects both precancer and cancer

There are a few key factors to consider before ordering your FIT test.

First, if you have insurance, decide if you prefer to use a test that accepts your coverage. If you don’t mind paying out of pocket, you may be able to consider more options.

Next, consider whether you’re comfortable directly handling stool or not. The sample collection process for some tests is more involved, while others are more flexible.

Finally, look at how long some companies take to give you results. Results may take just a few days or up to a couple of weeks in some cases. You can also opt for a kit like the one from Pinnacle Biolabs, which gives you results in minutes at home.

A FIT kit is a good choice for anyone who:

  • doesn’t have a history of colon cancer or IBD
  • doesn’t have siblings or parents who were diagnosed with colon cancer before age 60
  • has two or fewer relatives diagnosed at any age

Otherwise, it’s best to contact your doctor for a colonoscopy or sigmoidoscopy instead.

And regardless of risk factors, colonoscopy is the gold standard for colorectal cancer screening.

Other than being ready for a bowel movement, there’s no prep work required.

It’s best not to take stool tests during your menstrual period or while actively bleeding from hemorrhoids.

Most kits include similar instructions, but be sure to read yours carefully.

Some kits screen fully at home, without having to send in a sample to a lab to receive results. Some kits require direct contact with your stool and need you to send the sample for results. Make sure you know exactly what your kit will require of you before purchasing.

For kits that require you to send your sample for testing, make sure you write down any necessary information on your kit, including your name, the date, and so on.

After you have completed the necessary collection method, you’ll carefully package the materials in the provided box and follow instructions to send it for testing.

If your test result is negative, you can simply plan on doing another test in 1 year or when your healthcare team advises.

If your test result is positive, this means there is blood in your stool. Schedule an appointment with your doctor to look into it further.

Although FIT tests are a convenient way to screen for colon cancer from home, they are no substitute for talking with your doctor and getting a colonoscopy. This is especially true for those who are at high risk of colon cancer.

According to the Centers for Disease Control and Prevention (CDC), you might be at a higher risk if you have:

  • a history of IBD or colon cancer
  • parents or siblings with a history of colon cancer before age 60
  • two or more relatives who have had colon cancer at any age

There are a few other lifestyle-related risk factors for colon cancer to consider as well.

The CDC also reports that certain lifestyle changes may help reduce your risk.

These include:

The CDC recommends that people between ages 45 and 75 get checked regularly for colon cancer.

According to a 2021 review, only 67% of people in the United States are up to date with their colorectal cancer screening. The hope is that FIT may help bridge the gap in regular screening for those at average risk who may have less access to a colonoscopy or who simply prefer a less invasive and more convenient screening option.

Here are the main differences between colonoscopies and FITs.

Colonoscopies require more prep work

Colonoscopies are the benchmark method for testing for colon cancer, but they’re also considered a hassle for a few reasons. They generally require unpleasant prep work, diet or medication restrictions, and time off from work or school. And of course, while they’re not painful, they can be uncomfortable.

FITs must be done more frequently than colonoscopies

Although 2019 research shows FIT is nearly as effective as colonoscopies, one drawback is that you must do it yearly to detect colorectal cancer. This is much more frequent than the even more accurate, though uncomfortable, colonoscopies.

Colonoscopies are more accurate and a better choice if you’re at high risk

Those at high risk of colon cancer — including those with a family history, prior colon cancer diagnoses, or history of IBD, as well as other known risk factors — should get a colonoscopy.

Colonoscopies, like most procedures, have a few risks. A 2011 report from the American Society for Gastrointestinal Endoscopy (ASGE) states that there are fewer than 3 serious complications for every 1,000 procedures performed on people with an average risk of colorectal cancer, and a follow-up review from 2019 found that the level of risk had stayed the same over time.

Is an at-home FIT accurate?

One 2020 meta-analysis examining 44 studies showed that FIT tests correctly identified four out of five cases of colorectal cancer. These detected cases stages were II through IV.

It’s important to note that the test sensitivity was shown to be lowest for the earliest stages — with colon cancer, early detection is crucial.

While FITs are almost as useful as colonoscopies, these tests are still susceptible to user error.

Research from 2018 suggests there’s also a risk of false-positive and false-negative results.

According to the ASGE, FIT tests have a false positive rate of around 5%.

The ASGE also states that false positives and false negatives can happen with FIT-Fecal DNA tests.

Additionally, the ASGE adds that this type of test can fail to detect 8% of cancers and 60% of large polyps that are at higher risk of developing into colon cancer.

Colonoscopies are considered to be the gold standard. In other words, they may be the absolute best way to screen for colon cancer, especially for those who are at high risk.

Is a FIT test as good as a colonoscopy?

A 2019 review shows FITs are almost as effective as colonoscopies, but colonoscopies are considered the most accurate in screening. They’re even more precise, and they’re necessary for those with a high risk of colon cancer.

Is a FIT test the same as Cologuard?

A FIT test is a fecal immunochemical test, while Cologuard is a particular test. Cologuard is different compared with other FIT options, because it looks for certain DNA markers and can test for both precancer and cancer. Meanwhile, most FITs just test for the presence of blood.

It’s worth mentioning results from a small 2020 study that looked at Cologaurd’s accuracy compared to the FIT test method.

The study found that Cologaurd showed a 13.4% false-positive result rate. This is an increase of 8.3% compared to the FIT test method.

When should you take an at-home colon cancer test?

Doing a FIT once a year is a good option for those at average risk of colon cancer who want to avoid the hassle of a colonoscopy, have less access to colonoscopies, or prefer a less invasive screening option and don’t mind doing a FIT annually.

How can colon cancer be detected without a colonoscopy?

Colon growths and polyps in the large intestine that can become cancerous may cause bleeding. A FIT can detect unseen blood in the stool. Blood in the stool may signal the presence of these growths or polyps.

How does the FIT compare with the gFOBT?

The guaiac-based fecal occult blood test (gFOBT) is another type of test that detects blood in the stool.

Experts in a 2018 review considered FIT the better testing option for a couple of reasons. Not only is the FIT more effective at detecting blood in the stool, but it also doesn’t require any prep before testing.

Does insurance cover at-home FIT kits?

Insurance may cover some FIT kits, but it’s not a guarantee. If you have insurance, it’s a good idea to call your provider to find out about cost. If your insurance doesn’t cover the cost of FIT, some affordable options are available.

For those ages 45 years or older with Medicare, coverage is available for this test once every 12 months.

FIT kits test for blood in the stool, which is often a sign of colon cancer.

These tests come in a range of styles and prices. Some can fully screen at home, while some require you to send a sample to a lab for test results.

The FIT is a good option for those at average risk of colon cancer who would like to avoid the fuss of prep time and a doctor’s visit for a colonoscopy.

People at high risk of colon cancer should still undergo a colonoscopy.

Those who opt for the FIT will need to perform the test every year versus every 10 years for a colonoscopy.

Breanna Mona is a writer based in Cleveland, OH. She holds a master’s degree in media and journalism and writes about health, lifestyle, and entertainment.