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- Best FIT with subscription option: Everlywell
- Best FIT with fast lab results: LetsGetChecked
- Best FIT with good lab reputation: Pixel by Labcorp
- Best FIT to purchase in person: Pinnacle Biolabs
- Best FIT DNA test: Cologuard
Colonoscopies are about as exciting as a trip to the dentist or DMV — OK, maybe even less exciting.
But for those at average risk of colon cancer, there’s an easier, less invasive way to screen for the disease from home. Fecal immunochemical tests (FITs) are a good option for those:
- without a history of colon cancer or an inflammatory bowel disease
- without siblings or parents who have been diagnosed with colon cancer before age 60
- with no more than two relatives diagnosed at any age
Keep reading to learn more about these tests and see our picks for the best FIT options.
We looked for tests that:
- you can easily take at home
- are approved by the Food and Drug Administration (FDA)
- are made by companies that use College of American Pathologists (CAP) accredited and Clinical Laboratory Improvement Amendments (CLIA) certified laboratories
- are made by companies that offer good customer service and support
- $ = under $50
- $$ = $50–$100
- $$$ = over $100
Best FIT with subscription option
- Price: $$
Everlywell offers a range of at-home health tests, including a FIT kit.
A bonus of using this test is that Everlywell offers other services along with the test, like help with understanding results, the ability to chat with one of their physicians about test results, and other resources for colon cancer.
The drawback is that this kit requires you to handle stool to send it to one of Everlywell’s labs. This is done by using the brush provided in your kit. You’ll need to brush your stool for about 5 seconds before the brush is dabbed onto the test card, only transferring the water onto the card. This process is done again using a second brush.
Everlywell works only with labs that are CLIA certified, meaning the labs must meet high standards to get both state and federal certifications. Plus, these labs must also submit themselves to regular inspections.
Everlywell has a $24.99 per month membership program that offers access to a qualifying test every month. So, if you’d like to perform other health checks from home, like an HIV test or cholesterol test, Everlywell makes that easy.
Everlywell accepts health savings account (HSA) and flexible spending account (FSA) cards. They also offer free shipping for both receiving the kit and sending the sample.
Best FIT with fast lab results
- Price: $$
LetsGetChecked offers a slew of at-home health tests — 34 different tests to be exact.
Their FIT requires you to collect your stool sample for lab testing. After your bowel movement, you’ll gather the provided tube. Then, you’ll dip the sample stick end into your stool until the end of the stick is covered.
Finally, you’ll put the stick back into the provided tube and fasten the cap securely before placing the tube in the provided bag and box and then sending it off to the lab. The sample should be sent to the lab the same day it’s taken.
If your test is positive, LetsGetChecked might offer you a referral to a gastroenterologist or encourage you to visit your primary care physician for further testing.
One perk with this brand is that your results can be available in just 2 to 5 days.
This company also accepts HSA and FSA cards.
Best FIT with good lab reputation
- Price: $$
Labcorp has been around for more than 50 years. This network of CAP accredited and CLIA certified laboratories says they handle about 3 million patient samples every week.
For this test, you’ll register your kit online using the Pixel website. You’ll need to return your sample to FedEx (pickup or drop box) the same day you take it.
The website is a bit vague about how your sample is collected, but it does say that you’ll be provided with instructions, a wand, and capture paper.
A nice feature is that by purchasing the FIT, you have access to physician services from PWNHealth. You can expect to be contacted by the company if your test comes back positive. Since PWNHealth does receive test results, this could be considered a drawback for those who want results to remain private.
Best FIT to purchase in person
- Price: $
According to Pinnacle Biolabs, their test has been the bestselling colon cancer screening test in the United States for 6 consecutive years.
To perform this test, you’ll collect your stool sample using a tube with an attached wand. You’ll gather your stool with the wand and then put it back into the tube. Next, you’ll add three drops of the provided solution to the test cassette. The window on the test will give you your results in just 1 to 3 minutes.
Two lines indicate a positive test result (blood is present in the stool) and one line indicates a negative result.
You can buy it online or find it at major retailers. This test is tax-free and ships free.
Best FIT DNA test
- Price: $$$
This is a FIT DNA test, so it uses stool DNA technology to screen your stool.
The website explains that each day, your colon sheds cells that line it. During this routine, normal and altered cells are shed. During bowel movements, these cells are collected in your stool as it goes through the colon. The FIT DNA test identifies these cells to detect both precancer and cancer.
People between the ages of 50 and 75 may be able to get Cologuard without any out-of-pocket cost. For those without insurance, or insurance plans that don’t cover it, the maximum price for this test is $649.
This test is also FDA approved.
A FIT kit is a good choice for anyone who:
- doesn’t have a history of colon cancer or IBD
- doesn’t have siblings or parents who were diagnosed with colon cancer before age 60
- has two or fewer relatives diagnosed at any age
Otherwise, it’s best to see your doctor for a colonoscopy instead.
Other than being ready for a bowel movement, there’s no prep work required.
Most kits include similar instructions, but be sure to read yours carefully.
Some kits screen fully at home, without having to send in a sample to a lab to receive results. Some kits require direct contact with your stool and need you to send the sample for results. Make sure you know exactly what your kit will require of you before purchasing.
For kits that require you to send your sample for testing, make sure you write down any necessary information on your kit, including your name, the date, and so on.
After you have completed the necessary collection method, you’ll carefully package the materials in the provided box and follow instructions to send it for testing.
If your test result is negative, you can simply plan on doing another test in a year.
If your test result is positive, this means there is blood in your stool and you should schedule an appointment with your doctor to look into it further.
Here are the main differences between colonoscopies and FITs.
Colonoscopies require more prep work
Colonoscopies are the gold standard for testing for colon cancer, but they’re also considered a hassle for a few reasons. They generally require unpleasant prep work, diet or medication restrictions, time off from work or school, and of course, while they’re not painful, they can be uncomfortable.
FITs must be done more frequently than colonoscopies
Although research shows FIT is nearly as effective as colonoscopies, one drawback is that you must do it yearly to detect colorectal cancer. This is much more frequent than the even more accurate, albeit uncomfortable colonoscopies.
Colonoscopies are more accurate and a better choice for patients at high risk
Those at high risk for colon cancer — including those with a family history, prior colon cancer diagnoses, or history of inflammatory bowel disease, as well as other known risk factors — should get a colonoscopy.
Although colonoscopies, like most procedures, have a few risks, the American Society for Gastrointestinal Endoscopy reports that the risks are fewer than three serious complications for every 1,000 procedures performed on people with an average risk of colorectal cancer.
Is an at-home FIT accurate?
Research shows FITs are almost as effective as colonoscopies, but colonoscopies are considered the gold standard in screening. They’re even more accurate, and they’re necessary for those with a high risk of colon cancer.
When should you take an at-home colon cancer test?
Doing a FIT is a good option for those at average risk of colon cancer who are looking to avoid the hassle of a colonoscopy, who have less access to colonoscopies, or who just prefer a less invasive screening option and don’t mind doing a FIT kit every year.
How can colon cancer be detected without a colonoscopy?
Colon growths and polyps in the large intestine that can become cancerous may cause bleeding. FIT can detect unseen blood in the stool that may signal the presence of these growths or polyps.
How does the FIT compare with the gFOBT?
The Guaiac-based fecal occult blood test (gFOBT) is another type of test that detects blood in the stool.
The FIT is considered the better testing option for a couple of reasons. Not only is the FIT more effective at detecting blood in the stool, but it also doesn’t require any prep before testing.
Does insurance cover at-home FIT kits?
Insurance may cover some FIT kits, but it’s not a guarantee. It’s a good idea to call your insurance provider to find out about cost. If your insurance doesn’t cover the cost of FIT, some affordable options are available.
FIT kits test for stool in the blood, which is often a sign of colon cancer.
These tests come in a range of styles and prices. Some can fully screen at home, while some require you to send a sample to a lab for test results.
The FIT is a good option for those at average risk of colon cancer who would like to avoid the fuss of prep time and a doctor’s visit for a colonoscopy.
People at high risk of colon cancer should still undergo a colonoscopy.
Those who opt for the FIT will need to perform the test every year versus every 10 years for a colonoscopy.
Breanna Mona is a writer based in Cleveland, OH. She holds a master’s degree in media and journalism and writes about health, lifestyle, and entertainment.