Amlodipine is a medication that doctors prescribe to treat high blood pressure and reduce chest pain. Pharmacies in the United States fill
While taking amlodipine can be good for your heart health, some people may be concerned about its side effects, including potential liver damage.
This article will explore whether amlodipine can harm your liver. It will also include liver-friendly tips no matter what medications you’re taking.
Your liver contains enzymes that break down other proteins so your body can absorb them. It helps turn food into energy and removes toxins from your body.
These enzymes also break down many medications, including amlodipine. Cytochrome p450 enzymes break down amlodipine into its parts. This enables amlodipine to work in your body and for your body to then discard the waste portions.
Damage to your liver can cause it to release some enzymes into your bloodstream.
People who take amlodipine may experience a
In the very few published reports, the liver injury typically occurred
Fortunately, there are no reports of amlodipine causing long-term liver damage. Symptoms usually go away when you stop taking the medication.
Nonalcoholic fatty liver disease (NAFLD) occurs when you have more fat than is typical in your liver. Too much fat can contribute to later liver damage. About
Research has not shown amlodipine to contribute to NAFLD. In fact, according to a
Currently, there are no medications that treat NAFLD. But doctors often search for medications that may help reduce the risks of liver damage.
The study found amlodipine improved lipid (fat) metabolism in mice. It promoted the growth of beneficial bacteria in the gut and the breaking down of compounds that otherwise lead to the progression of NAFLD.
While this is promising research, human trials will be needed before we know if amlodipine can have protective benefits against NAFLD.
So can people with NAFLD safely take amlodipine for high blood pressure?
While there are some reports of liver complications from amlodipine, they’re
For this reason, your doctor will likely consider it safe to prescribe amlodipine even if you have NAFLD.
People with liver disease can typically take amlodipine safely. Your doctor should review potential side effects related to taking amlodipine. These may include:
- heart palpitations
Liver toxicity is an uncommon side effect for patients with or without liver disease.
Amlodipine is a medication that can help lower your blood pressure. While amlodipine can cause side effects, liver disease is an uncommon one.
One animal study also found taking amlodipine could potentially improve fatty liver disease.
If your doctor prescribes amlodipine, it’s important to consider the risks and benefits so you can take it as safely as possible.