Highlights for Entyvio
Entyvio is used to treat Crohn’s disease and ulcerative colitis in adults. It helps reduce inflammation (swelling and irritation) in the gastrointestinal (GI) tract.
Entyvio comes as an intravenous (IV) infusion. This means it’s injected into your vein. It’s only given by a healthcare provider in a healthcare facility.
Entyvio is a brand-name drug. It’s not available as a generic drug.
The more common side effects of taking Entyvio include headache, joint pain, nausea, fever, and upper respiratory tract infection.
Before starting Entyvio, you should make sure all of your vaccinations are up to date.
Progressive multifocal leukoencephalopathy (PML) See Details
What is Entyvio?
This drug is a prescription medication. It comes as an intravenous (IV) drug. This means it’s injected into your vein. This medication is only given by a healthcare provider in a healthcare facility.
This drug is available as a brand-name drug called Entyvio. It’s not available as a generic drug.
This drug may be used as part of a combination therapy. This means you may need to take it with other medications.
Why it's used
This drug is used to treat the symptoms of both ulcerative colitis (UC) and Crohn’s disease. It’s used to treat moderate-to-severe, active disease. This drug is used when certain other medications have not worked well enough.
How it works
This drug belongs to a class of drugs called integrin receptor antagonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Entyvio Side Effects
More Common Side Effects
The more common side effects that can occur with use of Entyvio include:
pain in the arms or legs
feeling tired or weak
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious Side Effects
Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Serious allergic reactions. Symptoms can include:
- swelling of your lips, tongue, throat, or face
- shortness of breath or trouble breathing
- feeling hot
- heart palpitations (very rapid or irregular heartbeat)
Infections. Symptoms can include:
- muscle aches
- shortness of breath
- runny nose
- sore throat
- red or painful skin sores on your body
- pain during urination
Progressive multifocal leukoencephalopathy (PML). Symptoms can include:
- confusion or trouble thinking
- loss of balance
- changes in the way you walk or talk
- decreased strength or weakness on one side of your body
- blurred vision or loss of vision
Liver problems. Symptoms can include:
- loss of appetite
- pain on the right side of your abdomen (stomach area)
- dark-colored urine
- yellowing of your skin and whites of your eyes
This drug doesn’t cause drowsiness. But it can cause a serious allergic reaction. This can occur shortly after you receive your infusion. Your doctor will monitor you for symptoms of an allergic reaction while you are receiving this medication.
Entyvio May Interact with Other Medications
Entyvio can interact with other medications, herbs, or vitamins you might be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Your healthcare provider will look out for interactions with your current medications. Always be sure to tell your doctor about all medications, herbs, or vitamins you’re taking.
How to Take Entyvio (Dosage)
Your doctor will determine a dosage that’s right for you based on your individual needs. Your general health may affect your dosage. Tell your doctor about all health conditions you have before your healthcare provider administers the drug to you.
This drug comes with risks if you don’t take it as prescribed.
If you stop taking the drug suddenly or don’t take it at all
Your symptoms of UC or Crohn’s disease may get worse. These can include diarrhea, constipation, rectal bleeding, an urgent need to move your bowels, or abdominal cramps.
If you miss doses or don’t take the drug on schedule
Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.
What to do if you miss a dose
Call your doctor right away to reschedule your appointment to receive this drug.
How to tell if the drug is working
Your symptoms of UC or Crohn’s disease should improve.
This drug is used for long-term treatment.
- Taketa Pharmaceuticals America, Inc. (2014). Entyvio – vedolizumab [package insert]. Deerfield, IL.
Content developed in collaboration with University of Illinois-Chicago, Drug Information Group
Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on November 11, 2015