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Generic Name:

secukinumab, Injectable solution

Cosentyx

Cosentyx

Generic Name: secukinumab, Injectable solution

All Brands

  • Cosentyx
SECTION 1 of 4

Highlights for Cosentyx

Injectable solution
1

Cosentyx is used to treat moderate to severe plaque psoriasis. It’s used in adults with psoriasis that covers a large area or many areas of the body.

2

This drug comes as a solution in a prefilled pen or prefilled syringe for injection. You or your caregiver may give this drug at home. It’s also available as a powder that’s made into a solution for injection. The solution made from a powder is only injected by a healthcare provider. Your doctor will decide which form of this drug is best for you.

3

Cosentyx is a brand name for the drug secukinumab. This drug is not available as a generic drug.

4

The more common side effects of this drug can include cold symptoms, upper respiratory infections, and diarrhea.

5

In some cases, Cosentyx can cause serious side effects. These include lowering the ability of your immune system to fight off infections. This side effect may increase your risk of infections.

IMPORTANT INFORMATION

Infections

This drug may lower your immune system’s ability to fight off infections. This may increase your risk of infections. If you think you have an infection, call your doctor right away. Symptoms may include fever, chills, muscle aches, cough, shortness of breath, and blood in your phlegm. Symptoms can also include weight loss, sores on your body, diarrhea, stomach pain, or a burning sensation when you urinate. Your doctor may have you stop taking this drug until your infection heals.

Live vaccines

You shouldn’t receive live vaccines while taking this drug. This drug can weaken your immune system. Your immune system may not be strong enough to receive a live vaccine. Examples of live vaccines include the varicella (chickenpox) vaccine, shingles vaccine, and measles, mumps, and rubella vaccine.

What is Cosentyx?

This drug is a prescription drug. It’s available as an injectable solution in a prefilled pen or prefilled syringe. It’s self-injectable. This means that you or your caregiver may give the drug at home. It’s also available as a powder that’s made into a solution for injection by a healthcare provider.

Cosentyx is a brand name for the drug secukinumab. This drug is not available as a generic drug.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

This drug is used to treat moderate to severe plaque psoriasis. With this condition, your body makes skin cells too quickly, causing red, scaly patches of skin.

More Details

How it works

This drug belongs to a class of drugs called biologics or immunomodulators. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

More Details

Why it's used

This drug is used to treat moderate to severe plaque psoriasis. With this condition, your body makes skin cells too quickly, causing red, scaly patches of skin.

This drug is used in adults with psoriasis that covers a large area or many areas of the body.

How it works

This drug belongs to a class of drugs called biologics or immunomodulators. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

This drug works by targeting the action of a protein in your body called IL-17A. This protein causes inflammation and skin plaques. Blocking the activity of this protein decreases inflammation, itching, and the formation of skin plaques. This helps treat your plaque psoriasis.

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SECTION 2 of 4

Cosentyx Side Effects

Injectable solution

More Common Side Effects

The more common side effects of Cosentyx can include:

  • Cold symptoms. These can include:

    • runny nose
    • congested nose
    • sneezing
    • cough
    • sore throat
  • Upper respiratory infections, such as bronchitis, laryngitis, and sinusitis

  • Diarrhea

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious Side Effects

Call your doctor right away if you have serious side effects. Call 9-1-1 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • Crohn’s disease flare-ups. If you have Crohn’s disease, this drug can make your symptoms worse. Symptoms can include:

    • stomach pain or cramping
    • diarrhea
    • bloody stools
    • weight loss
  • Serious allergic reactions. Symptoms can include:

    • feeling faint
    • swelling of your face, eyelids, lips, mouth, tongue, or throat
    • trouble breathing or throat tightness
    • chest tightness
    • skin rash
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

This drug doesn’t cause drowsiness.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
SECTION 3 of 4

Cosentyx May Interact with Other Medications

Injectable solution

Cosentyx can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Medications that might interact with this drug

Drugs you should not use with Cosentyx

Do not take these drugs with Cosentyx. Doing so can cause dangerous effects in the body. Examples of these drugs include:

  • Live vaccines, such as the varicella (chickenpox) vaccine, shingles vaccine, and measles, mumps, and rubella vaccine. You shouldn’t receive live vaccines while taking this drug. Your immune system may not be strong enough to receive a live vaccine. You may be more prone to an infection. Tell your doctor if you’ve recently received or plan to receive a vaccine before starting this drug.

Interactions that increase your risk of side effects or make your drugs less effective

Taking Cosentyx with certain medications can increase or decrease the amount of the other drug in your body. This can raise your risk of side effects from these drugs or make these drugs not work as well. Examples of these drugs include:

  • Warfarin. Your doctor will monitor your blood levels of warfarin. This includes your international normalized ratio (INR). Your doctor may adjust your warfarin dose.
  • Cyclosporine. Your doctor will monitor your blood levels of this drug to make sure it’s at a normal level. Your doctor may adjust your cyclosporine dose.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Drug warnings
infections
People with infections

This drug may lower your immune system’s ability to fight off infections. This may increase your risk of infection. If you’re being treated for an infection, have an infection that doesn’t go away, or have an infection that keeps coming back, tell your doctor before starting this drug.

tuberculosis
People with tuberculosis (TB)

If you have an active TB infection, you shouldn’t take this drug. If you have a dormant form of TB or if your doctor feels you’re at risk for TB, they may give you medications to treat TB before starting you on this drug. You should also let your doctor know if you’ve been in close contact with someone who has TB.

crohn's disease
People with Crohn's disease

This drug can cause Crohn’s disease flare-ups. These flare-ups can be serious. Tell your doctor if your Crohn’s disease symptoms get worse while you’re taking this drug.

latex sensitivity
People with a sensitivity to latex

Let your doctor know if you’re allergic to latex. The needle cap on the pen and prefilled syringe of this drug contain latex.

pregnant women
Pregnant women

This drug is a category B pregnancy drug. That means two things:

  1. Research in animals has not shown a risk to the fetus when the mother takes the drug.
  2. There aren’t enough studies done in humans to show if the drug poses a risk to the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. Animal studies do not always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed.

breastfeeding
Women who are breast-feeding

It isn’t known if this drug passes into breast milk. If it does, it may cause side effects in a child who is breastfed.

Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

for children
For children

This drug hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

allergies
Allergies

This drug can cause a severe allergic reaction. Symptoms can include:

  • feeling faint
  • swelling of your face, eyelids, lips, mouth, tongue, or throat
  • trouble breathing or throat tightness
  • chest tightness
  • skin rash

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

SECTION 4 of 4

How to Take Cosentyx (Dosage)

Injectable solution

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

What are you taking this medication for?

Plaque psoriasis

Brand: Cosentyx

Form: Injectable solution: single-use injectable prefilled pen
Strengths: 150 mg/mL
Form: Injectable solution: single-use injectable prefilled syringe
Strengths: 150 mg/mL
Adult dosage (ages 18 years)
  • Typical starting dose: Inject 300 mg subcutaneously (under your skin). You can inject it in your upper arms, thighs, or stomach. You’ll give 2 injections per dose. Choose a new injection site each time you use it. You’ll inject one dose once per week for the first 5 weeks. After that, you’ll inject one dose once per month.
  • Dose changes: Some people may need a dose of 150 mg. Your doctor will decide the best dose for you. If your dose is 150 mg, you’ll give one injection per dose.  
Child dosage (ages 0–17 years)

It hasn’t been confirmed that this drug is safe and effective for use in people younger than 18 years.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always to speak with your doctor or pharmacist about dosages that are right for you.
Pharmacist's Advice
Clinical Associate Professor, University of Illinois at Chicago College of Pharmacy

This drug comes with risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all

Your symptoms of plaque psoriasis may not get better or may get worse. Symptoms include:

  • itchiness
  • pain
  • thick, red patches of skin
  • silver or white patches and scales

If you miss doses or don’t take the drug on schedule

Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much

You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

  • diarrhea
  • cold and flu-like symptoms
  • infections

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 9-1-1 or go to the nearest emergency room right away.

What to do if you miss a dose

Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working

Your symptoms of plaque psoriasis should get better.

This drug is used for long-term treatment.

Important considerations for taking this drug

Store this drug carefully

  • Store this drug the refrigerator. Keep it between 36°F and 46°F (2°C and 8°C). Take it out of the refrigerator 15–30 minutes before you’re ready to use it. The drug should be at room temperature when you inject it.
  • Keep this drug in the carton it comes in until you’re ready to use it. The carton will protect it from light.
  • Don’t freeze this drug.
  • Don’t shake this drug.

A prescription for this medication is refillable

You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

  • Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
  • Don’t worry about airport x-ray machines. They can’t hurt your medication.
  • You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled box with you.
  • Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.
  • This medication needs to be refrigerated. You may need to use an insulated bag with a cold pack to maintain the temperature when traveling.
  • You may need needles and syringes to take this drug. Check for special rules about traveling with medication, needles, and syringes.

Self-management

Your healthcare provider will show you the right way to prepare and inject this drug. You shouldn’t try to inject this drug yourself until a healthcare provider has trained you or your caregiver on how to do so.

This drug is an injectable solution that comes as a single-use, ready-to-use injectable prefilled pen or an injectable prefilled syringe. You don’t need to mix or dilute the solution. Use one new pen or syringe for each injection. Follow your healthcare provider’s directions for use.

Clinical monitoring

You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:

  • Infection. Call your doctor if you think you have an infection or have symptoms of an infection. Symptoms can include:
    • fever, sweats, or chills
    • muscle aches
    • cough
    • shortness of breath
    • blood in your phlegm
    • weight loss
    • warm, red, or painful skin or sores on your body
    • diarrhea or stomach pain
    • burning sensation when you urinate
    • more frequent urination than normal
  • Crohn’s disease flare-ups. If you have Crohn’s disease, watch for signs that your condition is getting worse. These signs can include:
    • stomach pain or cramping
    • diarrhea
    • bloody stools
    • weight loss

Hidden costs

You’ll need to dispose of your used syringes in a sharps container (a designated bin for safe disposal of used syringes) right after you use them. Don’t discard the syringes and needles in your household trash. If you don’t have an sharps container, you may use a container that meets these standards:

  • made of a heavy-duty plastic
  • closes with a tight-fitting, puncture-resistant lid that doesn’t let syringes stick out
  • stands upright and won’t tip over
  • doesn’t leak
  • labeled “hazardous waste inside the container”

Examples of these containers include coffee canisters, milk jugs, and plastic laundry detergent containers. These must be sturdy and have a tight lid. 

You’ll also need:

  • alcohol wipes
  • cotton balls or gauze

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.


Show Sources

Content developed in collaboration with University of Illinois-Chicago, Drug Information Group

Medically reviewed by Creighton University, Center for Drug Information and Evidence-Based Practice on January 6, 2016

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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