The human gut is a complex system that majorly impacts the body’s overall health. 

Consuming probiotics is one way to support a healthy gut and keep your body functioning well. 

Probiotics are live microorganisms that have multiple strains, only some of which you can get from food. Supplementing with additional probiotics may help support your immune, digestive, and overall health. 

Akkermansia muciniphila is an example of strain that you can most efficiently get through supplementation, and it’s an important one.

Researchers found that the Akkermansia muciniphila strain is naturally lower in people with health conditions that may affect blood sugar and intestinal health. 

What is Akkermansia muciniphila?

Akkermansia is a novel probiotic strain discovered in 2004. Typically, it makes up 3–5% of the intestinal bacteria (though some people don’t have it), it is specifically found in the mucus layer of the large intestines and helps regulate the gut lining, which is vital for a healthy gut microbiome. 

The name “muciniphila” translates to “like mucin.” Mucin is made up of protein and plays an essential protective role in the gastrointestinal tract. A damaged mucus layer can increase a person’s risk of infection or health conditions.

You can buy Akkermansia through the medical probiotic company Pendulum Therapeutics, the only brand currently offering an Akkermansia probiotic.

What is the microbiome?

Sleep, exercise, and a healthy diet are vital for overall health, but scientists are also discovering the importance of a healthy gut microbiome — the trillions of microorganisms such as bacteria, viruses, and fungi that coexist in our body and perform essential tasks.

These tasks include maintaining a robust immune system, preventing infections, and aiding with digestion.

The gut microbiome is always changing due to diet, stress, antibiotics, and other factors – which can lead to the loss of certain beneficial bacteria. Pendulum probiotics target the gut microbiome by introducing beneficial bacteria back into the ecosystem.

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How is Akkermansia different from other probiotics?

Akkermansia’s origin makes it different from other popular probiotics. 

“Unlike probiotic strains such as lactobacillus that can be found in foods like yogurt, [Akkermansia] is a beneficial bacteria that is natural to our bodies,” says Tara Karr, MS, RD, LDN, CDCES, nutrition educator, and registered dietitian for Pendulum Therapeutics.  

“In fact, it’s even found in the gut of healthy infants,” says Karr. “It is unclear why some people have this strain in their guts, and others don’t. Once the beneficial bug Akkermansia goes missing from the gut, the most direct way to recover it is through supplementing with the actual strain itself!”

Akkermansia has been studied in over 1,000 scientific publications. But only Pendulum has taken the charge and patented a strain of Akkermansia muciniphila in its products.

With this patent, Pendulum has created an easy-to-swallow capsule. 

A unique delivery system

Some strains of probiotics are unable to survive exposure to stomach acid and cannot efficiently travel to the large intestine. 

Pendulum’s probiotic has a unique, acid-resistant coated capsule that supports its absorption into the large intestine and provides essential health benefits. 

If you’re looking to add Akkermansia to your daily routine, you can only find it at Pendulum Therapeutics. You should take it once daily with food to ensure the probiotic makes it to your gut microbiome. Save 20% on your first month of membership with code HEALTHLINE20 at

Akkermansia benefits

The bacteria in probiotics are known to help produce vitamins, aid in digestion, fight against disease-causing cells, and reduce certain health conditions. 

Akkermansia is a strain of probiotic known to maintain intestinal integrity by helping to thicken and restore the gut’s lining and maintain a healthy digestive system. 

“I like to think of Akkermansia as a gatekeeper of our microbiome,” says Karr. “Just like you don’t want any holes in your fence, you also don’t want any ‘holes,’ or weak spots, in your gut lining.”

Studies show that people with a healthy gut may have higher amounts of Akkermansia. Higher levels of Akkermansia in the gut are associated with the ability to maintain a healthy weight

There are no known side effects to taking Akkermansia, but make sure to check with your doctor before trying a new supplement, especially if you’re taking any medications. 


Do good bacteria exist?

Yes! Not all bacteria is bad. Certain strains are critical for overall health.

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Bottom Line

Gut health is important for your overall health. Taking probiotics is a great way to keep the gut and body healthy. 

You can feel confident choosing Pendulum for your probiotic needs, knowing that you’re getting a next-generation strain like Akkermansia muciniphila that can help you maintain a healthy gut microbiome.  

Pendulum Akkermansia holds a patented strain of Akkermansia muciniphila; and is one of the unique strains discovered through high-resolution DNA sequencing. This next-generation bacterial strain has been linked to helping with improved gut health by strengthening and regulating the gut lining, which is critical for overall health.

Save 20% on your first month of membership with code HEALTHLINE20


Amandine Everard, et al. (2013). Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.

National Center for Complementary and Integrative Health. (2019). Probiotics: What you need to know. 

National Institutes of Health Office of Dietary Supplements. (2021). Probiotics. 

Science Direct. (2019). Akkermansia.

Zhang T, Li Q, Cheng L, Buch H, Zhang F. (2019). Akkermansia muciniphila is a promising probiotic. Microb Biotechnol. 

Zhou K. (2017). Strategies to promote abundance of Akkermansia muciniphila, an emerging probiotics in the gut, evidence from dietary intervention studies. J Funct Foods.