Osteoporosis is a common problem that can lead to broken bones as women age. To reduce this risk, m...
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Osteoporosis is a common problem that can lead to broken bones as women age. To reduce this risk, millions of women take calcium supplements. After being broken down in the stomach, the calcium is absorbed in the small intestine and transported through the bloodstream to bones and other tissues. 99% of the calcium in your body is stored in your bones and teeth, and calcium supports their structure and function. To prevent loss of bone mass, it's important to have enough calcium in the blood transported to bones. There is concern that this goal may be hindered by long-term or chronic use of the drugs called proton pump inhibitors - or PPIs. PPIs shut down the pumps in stomach cells that make stomach acid. Women who use them long-term have an increased risk of fractures. It is thought that reduced stomach acid may slow the breakdown of calcium in the stomach and reduce the amount absorbed from the small intestine. This would reduce the amount of calcium in the bloodstream and the amount being absorbed by bones, and could contribute to bone thinning or osteoporosis.