Generally, the first problem to develop in someone with type 2 diabetes is a condition called insul...
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Generally, the first problem to develop in someone with type 2 diabetes is a condition called insulin resistance. This means that glucose - a form of sugar - can't enter cells the way it should. Glucose is formed from the breakdown of foods, especially carbohydrates. Normally, glucose attaches to cells of the pancreas, which triggers the cells to produce a hormone called insulin. The insulin attaches to receptors on the membrane of most cells in the body. This allows the glucose to enter the cell, to be used for fuel. In people with insulin resistance, the insulin can still attach normally to the receptors on these cells. But various mechanisms prevent the insulin from moving the glucose into the cells to be used for fuel. When the glucose can't enter cells as it should, blood levels of glucose rise to abnormally high levels. This problem is called hyperglycemia.