Follow on Twitter Follow on Facebook
Symptom Search   |   Treatment Search   |   Doctor Search   |   Drug Search

Drug Notebook

Media Gallery
Drug Info Tools
Search by color, shape and markings. click here
Check any 2 drugs for interactions. click here
Compare any two drugs side by side. click here
Medicare's drug plans are subsidized by the US federal government and offered through insurers.
Advertisement
Marketplace
Licensed from
APAP/butalbital/caffeine/codeine
(a set a MEE noe fen; byoo TAL bi tal; KAF een; KOE deen)

What is this medicine?
ACETAMINOPHEN; BUTALBITAL; CAFFEINE; CODEINE (a set a MEE noe fen; byoo TAL bi tal; KAF een; KOE deen) is a pain reliever. It is used to treat tension headaches.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

Back to Top

What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • anxiety, irritable, excited
  • difficulty passing urine
  • breathing problems
  • confusion
  • fast, irregular heartbeat
  • feeling faint or lightheaded
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • seizures
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation
  • drowsiness, dizziness
  • dry mouth
  • headache
  • nausea, vomiting
  • passing urine more often
  • stomach pain

Back to Top

How should I use this medicine?
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

Back to Top

What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Back to Top

What may interact with this medicine?
Do not take this medicine with any of the following medications:

  • alcohol
  • linezolid
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • narcotic pain relievers
  • procarbazine
  • voriconazole

This medicine may also interact with the following medications:

  • antihistamines for allergy, cough and cold
  • barbiturates like phenobarbital
  • naltrexone
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • medicines used for sleep during surgery
  • muscle relaxers
  • other medicines with acetaminophen

Back to Top

What should I watch for while using this medicine?
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take the medicine for a long time.

Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine may cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

Many non-prescription medicines contain acetaminophen as an ingredient. Always read the labels carefully to avoid taking an accidental overdose, which can be dangerous.

Back to Top

What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:

  • breathing problems
  • drink more than 3 alcohol containing drinks per day
  • drug abuse or addiction
  • liver disease
  • intestinal problem
  • porphyria
  • recent head injury
  • an unusual or allergic reaction to acetaminophen, butalbital or other barbiturates, caffeine, codeine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

Back to Top

Can I stop taking the medication if I feel better?
If you are taking an analgesic for pain and you are no longer experiencing the pain you may stop using the medication. In general, pain medications are to be used on an ?as needed? basis.

Back to Top

I am on so many medications; do I have to take them all?
This is called polypharmacy—many different medications being used at the same time by one person. Sometimes, being on multiple medications is acceptable and appropriate but at other times it may be problematic. If you are receiving your medications from multiple physicians you need to ensure that they all know what medications you are taking. The best way to do this is to make a list of all the medications you are currently using, including all nutritional supplements, homeopathic remedies, vitamins and over-the-counter drugs (if possible, also include all the diseases you have been diagnosed with). Give a copy to every doctor who takes care of you so they have it on file, this way they can avoid duplicating medications and perhaps even try to consolidate some. After every doctor's visit remember to update the list accordingly. Also, as much as you possibly can, try to use the same pharmacy to fill all your prescriptions, this way any potential drug interactions can be caught and averted.

Back to Top

Back to Top