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What causes painful urination? 34 possible conditions

See a list of possible causes in order from the most common to the least.


Chronic Nonbacterial Prostatitis

Chronic nonbacterial prostatitis causes pain and inflammation in the prostate and the lower urinary tract in men. It's a common condition, especially in men between the ages of 35 and 50 and the cause is often unknown.

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Chlamydia Infection

Chlamydia is a sexually transmitted disease that should be treated quickly in order to avoid complications. It is caused by bacteria that are usually spread through sexual contact. People with chlamydia often don't hav...

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Orchitis is the inflammation of the testicles. It can be caused by either bacterial or viral infection such as the mumps or certain STIs. Symptoms are often restricted to just one testicle in most men.

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Reactive Arthritis (Reiter's Syndrome)

Reiter's syndrome produces inflammation, swelling, and pain in the joints due to infection elsewhere in the body. Symptoms include mouth ulcers, painful urination, and urethral discharge.

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Benign Enlargement of Prostate

Benign enlargement of the prostate, or benign prostatic hyperplasia, is a common condition where the prostate gland swells beyond normal size. It is a normal condition of male aging but can interfere with urination.

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Transitional Cell Cancer (Malignant Neoplasm of Ureter)

Urine collects in the renal pelvis and is drained by the ureter into the bladder. When cancer develops in the renal pelvis or ureter, it begins in transitional cells, which line these organs.

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Prostate Cancer Overview

Learn prostate cancer information, causes, symptoms and treatments.

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Endometrial Cancer (Cancer of the Uterine Endometrium)

Endometrial cancer is a type of cancer that starts in the inner lining of the uterus. You are at greater risk if you are 60-70 years old and have used hormone replacement therapy that contains estrogen.

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Genital Herpes

Genital herpes is a sexually transmitted infection (STI). This STD causes herpes sores, which are painful blisters (fluid-filled bumps) that can break open and ooze fluid. According to the Centers for Disease Contro...

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Vulvar Cancer

Vulvar cancer is a cancer of the vulva or a woman's external genitalia. The vulva is comprised of the inner and outer lips of the vagina, the clitoris, and the opening of the vagina. Some symptoms are vulvar itching...

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Acute Prostatitis

Acute prostatitis is the sudden onset of inflammation in the prostate. The prostate gland is a small, walnut-shaped organ located at the base of the bladder, in front of the rectum. The prostate provides 70 percent o...

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Hydronephrosis is a condition that typically occurs when one kidney becomes swollen due to the failure of normal drainage of urine from the kidney to the bladder. This swelling most commonly affects only one kidney, bu...

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Cystitis is inflammation of the bladder. It's most often caused by a bacterial infection known as a urinary tract infection (UTI). It can become a serious health issue if the infection spreads to the kidney.

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Acute Infective Cystitis

Acute infective cystitis is an inflammatory condition in your urinary tract system that can affect your bladder or the lower portion of your urinary tract. It is usually caused by a bacterial infection.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.