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What causes pain and swollen lymph nodes? 26 possible conditions

See a list of possible causes in order from the most common to the least.

1

Lymphangitis

Lymphangitis is an inflammation of the lymphatic system, which is part of your immune system. If left untreated, the condition can become serious.

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2

Hodgkin's Disease

Learn more about a type of blood cancer called Hodgkin's disease (HD), including its symptoms, causes, diagnosis, and treatments.

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3

Non-Hodgkin’s Lymphoma

Non-Hodgkin's lymphoma (NHL) is a cancer of the lymphatic system that occurs when tumors develop from the lymphocytes, which are a type of white blood cell.

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4

Leukemia

Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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5

Infectious Mononucleosis

Infectious mononucleosis, or mono, refers to a group of symptoms usually caused by the Epstein-Barr virus (EBV).

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6

AIDS

If left untreated, HIV can lead to AIDS. AIDS weakens your immune system to the point where it can no longer fight off disease and infection. Learn more.

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7

Acute HIV Infection

Acute HIV infection occurs soon after someone is infected with HIV. Learn about its symptoms, diagnosis, treatment, and prevention.

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8

Systemic Lupus Erythematosus

Systemic lupus erythematosus, the most common form of lupus, is a chronic autoimmune disease that can cause severe fatigue and joint pain. Learn more about it.

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9

Shingles

Shingles is an infection caused by the varicella-zoster virus, which is the same virus that causes chickenpox. Chickenpox can live on in your nervous tissues.

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10

Sarcoidosis

Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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11

Burkitt's Lymphoma

Burkitt's lymphoma is a relatively rare and aggressive form of non-Hodgkin lymphoma.

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12

Kawasaki Disease

Early treatment is key to treating Kawasaki disease, especially in children. Learn how to recognize the symptoms of Kawasaki disease and when to see a doctor.

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13

Toxoplasmosis

Toxoplasmosis is an infection caused by a parasite. This parasite, called Toxoplasma gondii, can be found in cat feces and in undercooked meat.

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14

Juvenile Rheumatoid Arthritis

Juvenile rheumatoid arthritis is the most common type of arthritis in children. Learn about juvenile rheumatoid arthritis symptoms, diagnosis, and treatment.

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15

Sjogren's Syndrome

Sjögren's syndrome is an autoimmune disorder that primarily affects salivary and lacrimal glands. Read about signs and symptoms.

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16

German Measles (Rubella)

German measles, also known as rubella, is a viral infection. Learn about German measles symptoms, causes, diagnosis, treatment, and prevention.

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17

West Nile Virus Infection (West Nile Fever)

Learn about the causes and symptoms of the West Nile virus.

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18

Rheumatoid Arthritis Overview

Rheumatoid arthritis is an autoimmune disease. It causes joint problems. In autoimmune diseases, the immune system mistakes the body's own cells for invaders.

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19

Bites and Stings

Saliva from insect bites and venom from stings can cause a reaction such as swelling and itching. Bee stings can cause these symptoms and possibly anaphylaxis, a life-threatening condition.

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20

Marine Animal Bites or Stings

This condition is considered a medical emergency. Urgent care may be required.

Many marine animals bite or sting. Some animals are venomous, while others can inflict deep bites. Learn more about the risks and prevention.

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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