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What causes muscle pain and swollen lymph nodes? 15 possible conditions

See a list of possible causes in order from the most common to the least.



There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease and the most common type of lupus. One of its common symptoms is a rash on the cheeks and nose called a "butterfly rash."

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Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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Lymphangitis is an inflammation of the lymphatic system, which is part of the immune system. It is a network of organs, cells, ducts, and glands.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Rheumatoid Arthritis Overview

Rheumatoid arthritis (RA) is an autoimmune disease, a disease in which the immune system mistakes the body's own cells for invaders. In RA, the immune system attacks the synovia, the membranes lining the joints.

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Acute HIV Infection

Acute HIV infection is the primary stage of infection by the human immunodeficiency virus. There are several telltale symptoms, one of which is a rash.

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Dengue Fever

Dengue fever is a disease that affects much of the tropical region and is caused by one of four dengue viruses. A skin rash between two and five days after the initial fever is a common symptom.

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Toxoplasmosis is an infection caused by parasites found in cat feces and undercooked meat, symptoms of which include swollen lymph nodes and fever.

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German Measles (Rubella)

German measles, also known as rubella, is a rare viral condition. One of its symptoms is a pink rash that begins on the face and spreads downward.

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Adult-Onset Still's Disease

This relatively rare inflammatory condition begins with fever and may lead to arthritis. Women and people between the ages of 16 and 46 are most at risk.

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West Nile Virus Infection (West Nile Fever)

Spread by mosquitos, West Nile virus symptoms can vary in severity. Diarrhea and abdominal pain usually appears within two weeks of infection.

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The Plague

The plague is a serious bacterial infection that can be deadly. It's caused by poor sanitation, overcrowding, and large rodent populations.

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Brucellosis is a rare disease usually spread through ingesting infected raw meat and unpasteurized milk. Back pain, lethargy, chills, and fever may occur and could lead to complications.

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Weils Disease

Weil's disease is a severe form of the bacterial infection leptospirosis, which can lead to organ failure and bleeding. Symptoms include nausea, fever, headache, and jaundice.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.