Muscle pain, Rash: 26 Possible Causes
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  • Muscle pain
  • Rash

What causes muscle pain and rash? 26 possible conditions

See a list of possible causes in order from the most common to the least.


Systemic Lupus Erythematosus

Systemic lupus erythematosus, the most common form of lupus, is a chronic autoimmune disease that can cause severe fatigue and joint pain. Learn more about it.

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Dermatomyositis is a rare inflammatory disease. It's an inflammatory myopathy, which is a condition that occurs when your muscles become inflamed.

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Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease is a rare, often fatal illness. One of its late-stage symptoms is a bleeding rash over the entire body.

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Dengue Fever

Dengue fever is a disease that affects much of the tropical region and is caused by one of four dengue viruses. A skin rash between two and five days after the initial fever is a common symptom.

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Lyme Disease

Lyme disease is an infectious condition transmitted via tick bite. A "bull's eye" rash at the site of the bite is an early symptom of this disease.

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Colorado Tick Fever

Colorado tick fever is a viral infection transmitted through a bite from an infected tick. Learn about Colorado tick fever symptoms, diagnosis, and treatment.

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Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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Scarlet Fever

Scarlet fever is an infection that can develop in people who have strep throat. Learn about the symptoms, treatment, complications, and prevention of scarlet fever.

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MRSA (Staph) Infection

MRSA is an infection caused by a type of staph bacteria that's resistant to many different antibiotics. Learn about its symptoms, causes, and treatment.

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Fifth Disease

Fifth disease is common in children. It causes a red rash on the arms, legs, and cheeks, and a virus called parvovirus B19 causes it.

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Measles is a very contagious infection of the respiratory system. One of its several symptoms is a sore or swollen throat.

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Cellulitis is a common bacterial skin infection. Cellulitis may first appear as a red, swollen area that feels hot and tender to the touch.

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Porphyrias are rare types of genetic blood disorders in which patients have a defect in heme production, an important part of hemoglobin. Blisters are a sign of porphyria cutanea tarda, the most common type of porphyria.

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German Measles (Rubella)

German measles, also known as rubella, is a viral infection. Learn about German measles symptoms, causes, diagnosis, treatment, and prevention.

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Infectious Mononucleosis

Infectious mononucleosis, or mono, refers to a group of symptoms usually caused by the Epstein-Barr virus (EBV).

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Adult-Onset Still's Disease

Adult-onset Still's disease is an inflammatory condition causing swelling in joints, tissues, organs, and lymph nodes. Read more on this rare disease.

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The Atypical Facts About Atypical Pneumonia

Pneumonia is an infection that causes inflammation of the lungs. Atypical pneumonia is a kind that isn't caused by the bacteria that causes typical pneumonia.

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Poliomyelitis, or polio, is a highly contagious disease that is caused by a virus that attacks the body's nervous system.

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Typhus is caused by bacteria transmitted by flea, mite, louse, or tick bites. Scratching the bite opens the skin and allows the bacteria to enter the bloodstream.

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Acute HIV Infection

Acute HIV infection occurs soon after someone is infected with HIV. Learn about acute HIV infection symptoms, diagnosis, treatment, and prevention.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.