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What causes loss of capacity for enjoyment, poor self esteem and social withdrawal? 4 possible conditions

See a list of possible causes in order from the most common to the least.



There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Depression Overview

Depression is a mood disorder that can cause extreme and persistent feelings of sadness, hopelessness, and worthlessness. Depression type largely determines what kind of medical treatment is best.

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Postpartum Depression

Postpartum depression affects as many as 13 percent of new mothers. In the U.S., that's half a million women. Learn about symptoms, causes, risks, and more.

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Bipolar Disorder

Bipolar disorder mental illness marked by extreme from mania to depression. Bipolar disorder is also called bipolar disease or manic depression.

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Please consult a healthcare professional if you have health concerns.