Hepatomegaly: Causes, Symptoms & Consequences
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What causes liver enlarged? 15 possible conditions

Your liver is shaped somewhat like a football and is located in the upper right quadrant of your abdomen below your diaphragm and between your right nipple and the last rib on your right side. The liver is usually about 7.5 centimeters in women and 10.5... Read more

See a list of possible causes in order from the most common to the least.

1

Alcoholic Liver Disease

Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage o...

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2

Congestive Heart Failure (CHF)

Congestive heart failure (CHF) is a chronic condition that affects the chambers of your heart. CHF refers to fluid buildup around your heart.

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3

Cirrhosis

Cirrhosis is the severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections.

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4

Hepatitis

Hepatitis refers to an inflammatory condition of the liver. It's commonly caused by a viral infection, but there are other possible causes of hepatitis.

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5

Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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6

Hyperlipidemia

Cholesterol is a natural substance, but too much of it can clog blood vessels and lead to heart attack or stroke. High cholesterol levels can also cause yellow deposits in the eyes or in tendons.

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7

Chronic Lymphocytic Leukemia

Leukemia is a type of cancer that affects the blood and blood-forming tissues. There are many types of leukemia, each affecting different kinds of blood cells. Chronic lymphocytic leukemia, or CLL, is a cancer of th...

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8

Hepatic Vein Thrombosis (Budd-Chiari Syndrome)

Hepatic vein thrombosis (HVT) is an obstruction in the veins of the liver caused by a blood clot. This condition blocks blood flow from the liver to the heart.

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9

Familial Combined Hyperlipidemia

Familial combined hyperlipidemia is an inherited disorder that causes high cholesterol and high levels of triglycerides. Some individuals have no physical symptoms from the disease. For others, it may cause chest pain.

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10

Hyperlipoproteinemia Type IV

Hyperlipoproteinemia type IV leads to higher-than-normal triglyceride level due to a genetic defect. This may cause atherosclerosis and increase risk for certain heart conditions, including coronary artery disease.

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11

Gaucher's Disease

Gaucher disease is an inherited condition in which your body does not store fatty materials (called lipids) correctly. Fatty substances can build up around your vital organs, including your liver, spleen, lungs, bones...

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12

Metabolic Syndrome X

Metabolic syndrome X is a group of five risk factors that can increase your chance of developing cardiovascular diseases, such as heart disease, diabetes, and stroke. The risk factors include: increased blood pressure...

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13

Pericarditis

Pericarditis is the inflammation of the sac that surrounds your heart. The sac is a double-layered membrane called the pericardium. The pericardium protects your heart and helps it function properly.Pericarditis can b...

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14

Adult-Onset Still's Disease

This relatively rare inflammatory condition begins with fever and may lead to arthritis. Women and people between the ages of 16 and 46 are most at risk.

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15

Hyperlipoproteinemia

Hyperlipoproteinemia is a common disorder that results in high levels of lipids circulating in the blood. This can cause pancreatitis, abdominal pain, enlarged liver and other symptoms.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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