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What causes joint pain and swollen lymph nodes? 23 possible conditions

See a list of possible causes in order from the most common to the least.

1

AIDS

If left untreated, HIV can lead to AIDS. AIDS weakens your immune system to the point where it can no longer fight off disease and infection. Learn more.

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2

Systemic Lupus Erythematosus

Systemic lupus erythematosus, the most common form of lupus, is a chronic autoimmune disease that can cause severe fatigue and joint pain. Learn more about it.

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3

Rheumatoid Arthritis Overview

Rheumatoid arthritis is an autoimmune disease. It causes joint problems. In autoimmune diseases, the immune system mistakes the body's own cells for invaders.

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4

Sarcoidosis

Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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5

Leukemia

Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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6

Infectious Mononucleosis

Infectious mononucleosis, or mono, refers to a group of symptoms usually caused by the Epstein-Barr virus (EBV).

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7

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow. Learn about your risk factors and treatment options.

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8

Acute HIV Infection

Acute HIV infection occurs soon after someone is infected with HIV. Learn about its symptoms, diagnosis, treatment, and prevention.

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9

Chronic Myelogenous Leukemia (CML)

Leukemia is a type of cancer that starts in the blood or blood-forming tissues. There are many different types of leukemia, and treatment is different for each one. Chronic leukemias are slower growing than acut...

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10

Shingles

Shingles is an infection caused by the varicella-zoster virus, which is the same virus that causes chickenpox. Chickenpox can live on in your nervous tissues.

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11

Juvenile Rheumatoid Arthritis

Juvenile rheumatoid arthritis is the most common type of arthritis in children. Learn about juvenile rheumatoid arthritis symptoms, diagnosis, and treatment.

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12

Whipple's Disease

Bacteria cause Whipple's disease. This disease can make it difficult for your body to absorb nutrients. Learn about its symptoms.

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13

Kawasaki Disease

Early treatment is key to treating Kawasaki disease, especially in children. Learn how to recognize the symptoms of Kawasaki disease and when to see a doctor.

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14

Sjogren's Syndrome

Sjögren's syndrome is an autoimmune disorder that primarily affects salivary and lacrimal glands. Read about signs and symptoms.

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15

German Measles (Rubella)

German measles, also known as rubella, is a viral infection. Learn about German measles symptoms, causes, diagnosis, treatment, and prevention.

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16

West Nile Virus Infection (West Nile Fever)

Learn about the causes and symptoms of the West Nile virus.

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17

Adult-Onset Still's Disease

Adult-onset Still's disease is an inflammatory condition causing swelling in joints, tissues, organs, and lymph nodes. Read more on this rare disease.

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18

Brucellosis

Brucellosis is a disease caused by bacteria from the genus Brucella. Learn more about how this condition is spread, symptoms, and treatment.

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19

Weils Disease

Weil's disease is a severe form of the bacterial infection leptospirosis. Learn how to lower your risk of getting this potentially life-threatening illness.

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20

Dengue Fever

Dengue fever is a disease that affects much of the tropical region and is caused by one of four dengue viruses. A skin rash between two and five days after the initial fever is a common symptom.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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