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What causes irritable mood? 83 possible conditions

Irritability is a feeling of agitation. When you’re irritable, you become frustrated or upset easily. You might experience it in response to stressful situations. It may also be a symptom of a mental or physical health condition.  Read more

See a list of possible causes in order from the most common to the least.

1

Depression Overview

Depression is a mood disorder that can cause extreme and persistent feelings of sadness, hopelessness, and worthlessness. Depression type largely determines what kind of medical treatment is best.

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2

Middle Ear Infection

A middle ear infection (otitis media), occurs when a virus or bacteria causes the area behind the eardrum to become inflamed. It is most common in children.

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3

AIDS

There are many symptoms of HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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4

Low Blood Sugar (Hypoglycemia)

This condition is considered a medical emergency. Urgent care may be required.

Hypoglycemia, or low blood sugar, is a potentially dangerous condition that's most common in people with diabetes. Learn what causes it and how to prevent it.

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5

PMS (Premenstrual Syndrome)

Premenstrual syndrome causes a wide variety of emotional and physical symptoms. Learn more about it.

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6

Meningococcemia

This condition is considered a medical emergency. Urgent care may be required.

Meningococcemia is a bacterial infection that can lead to meningitis. Learn more about the symptoms.

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7

Colic and Crying

Colic is when your otherwise healthy baby cries for three or more hours a day, three or more times a week, for at least three weeks. Symptoms usually appear during your baby's first three to six weeks of life. A...

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8

Meningitis

This condition is considered a medical emergency. Urgent care may be required.

Meningitis is an inflammation of the meninges. This is the membrane that covers the brain and spinal cord. Meningitis may occur when fluid surrounding the meninges becomes infected. The most common causes of meningiti...

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9

Subarachnoid hemorrhage

This condition is considered a medical emergency. Urgent care may be required.

Subarachnoid hemorrhage (SAH) refers to bleeding within the subarachnoid space, which is the area between your brain and the tissues that cover it.

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10

Delirium

This condition is considered a medical emergency. Urgent care may be required.

Delirium is an abrupt change in the brain that causes mental confusion and emotional disruption. It makes it difficult to think, remember, sleep, pay attention, and more. You might experience the condition durin...

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11

Sleeplessness

Insomnia is a sleep disorder. Individuals who suffer from insomnia find it difficult to fall asleep, stay asleep, or both. They don't feel refreshed when they wake up from sleeping. This can lead to fatigue and othe...

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12

Fracture

This condition is considered a medical emergency. Urgent care may be required.

A fracture is a broken bone. Learn about the risk factors, symptoms, and treatments for different types of fracture.

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13

CFS (Chronic Fatigue Syndrome)

Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by extreme tiredness that can't be explained by an underlying medical condition.

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14

Anxiety

Learn more about anxiety with this overview of anxiety disorders.

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15

Cluster Headaches

Cluster headaches are severely painful and occur in cycles. Read more for tips on how to treat and relieve them.

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16

Generalized Anxiety Disorder

People who suffer from generalized anxiety disorder, or GAD, worry uncontrollably about common occurrences and situations. The condition may also be called chronic anxiety neurosis.GAD is different than normal feeling...

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17

Bipolar Disorder

Bipolar disorder is a mental illness marked by extreme shifts in mood ranging from mania to depression. It is also called bipolar disease or manic depression.

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18

Acute Stress Disorder

Acute stress disorder (ASD) may develop after a traumatic event, and it can last up to one month. Learn about the symptoms of ASD.

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19

Dementia Overview

Find out what you need to know about dementia, and learn how it's different from ordinary aging.

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20

Post Traumatic Stress Disorder (PTSD)

PTSD can affect anyone who has undergone a traumatic event. Read more on how to cope with it.

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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