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What causes general weakness and swollen feet? 17 possible conditions

See a list of possible causes in order from the most common to the least.



Bleeding or spotting, increased need to urinate, tender breasts, fatigue, nausea, and missed period are signs of pregnancy.

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The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause complications like obesity and heart disease.

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Obesity is defined as having a body mass index (BMI) of 30 or more. BMI is calculated using a person's weight and height. It can lead to other conditions like diabetes, heart disease, and cancer.

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Congestive Heart Failure (CHF)

Congestive heart failure is a chronic condition that affects the four chambers of the heart. Early symptoms include fatigue and weight gain. Irregular heart beat and wheezing indicate a worsening.

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Nutritional Deficiencies (Malnutrition)

A nutritional deficiency occurs when the body doesn't absorb the necessary amount of a nutrient. Symptoms include a pale complexion, fatigue, hair loss, and depression.

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Cellulitis is a common, often painful skin infection that first appears as a red, swollen area that feels hot and tender to the touch. If left untreated, it can become life-threatening.

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Rheumatoid Arthritis Overview

Rheumatoid arthritis (RA) is an autoimmune disease, a disease in which the immune system mistakes the body's own cells for invaders. In RA, the immune system attacks the synovia, the membranes lining the joints.

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PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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Hypertensive Heart Disease

Hypertensive heart disease refers to heart conditions caused by high blood pressure. Possible signs of acute hypertension include sweating and chills.

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Glomerulonephritis occurs when blood filtering vessels in the kidneys are damaged. This may contribute to kidney failure, which causes fatigue, insomnia, itchy skin, and other symptoms.

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Cirrhosis is severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections. Certain medications and disorder can also cause cirrhosis.

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Ischemic Cardiomyopathy

Ischemic cardiomyopathy is a condition that occurs when the heart muscle is weakened due to insufficient blood flow to the heart's muscle. This inhibits the heart's ability to pump blood and can lead to heart failure.

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Sickle Cell Anemia

Sickle cell anemia is a genetic disease that causes red blood cells to have an abnormal shape, causing blood flow problems. This can lead to tissue damage and pain, as well as enlarged spleen, anemia, and other symptoms.

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Infective Endocarditis

Infective endocarditis is an infection of the heart, normally caused by bacteria in the blood stream. It is a serious medical condition. If left untreated, the infection can damage your heart and may even cause death.

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Emphysema is a lung disease that, along with chronic bronchitis, represents a type of chronic obstructive pulmonary disease (COPD). Lack of oxygen may give skin and lips a bluish hue.

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ALS (Lou Gehrig's Disease)

Amyotrophic Lateral Sclerosis (ALS) is not contagious. It is a degenerative disease that affects the brain and spinal cord. A chronic disorder, it causes a loss of control of voluntary muscles. The nerves controllin...

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Teenage Pregnancy

Teenage pregnancy is pregnancy in a woman 19 years of age or younger. A woman can get pregnant if she has vaginal sex with a man at any age after she has started having regular monthly periods. Some signs of pregnanc...

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.