Let's see if we can figure out what's causing your symptoms.
Select additional symptoms and we'll narrow your results.

What causes general weakness and loss of appetite? 83 possible conditions

See a list of possible causes in order from the most common to the least.



The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause complications like obesity and heart disease.

Read more »


Cold and Flu Overview

Common colds and influenza are contagious infections that affect the respiratory system. Both are airborne illnesses, spread through coughing and sneezing. Shared symptoms include headache, cough, sore throat, and more.

Read more »



Bleeding or spotting, increased need to urinate, tender breasts, fatigue, nausea, and missed period are signs of pregnancy.

Read more »



There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

Read more »


Common Cold Overview

The common cold is a virus that involves symptoms like sneezing, a runny nose and a headache. Learn the causes, symptoms and treatments for the common cold now!

Read more »


PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

Read more »



Hepatitis refers to an inflammatory condition of the liver. It's commonly caused by a viral infection, but there are other possible causes of hepatitis.

Read more »


Heat Emergencies

This condition is considered a medical emergency. Urgent care may be required.

Heat emergencies are health crises caused by exposure to hot weather and sun. Heat emergencies have three stages: heat cramps, heat exhaustion, and heatstroke. All three stages are serious.

Read more »



Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

Read more »


Alcoholic Liver Disease

Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage o...

Read more »


Low Blood Sodium (Hyponatremia)

Low blood sodium, or hyponatremia, occurs when water and sodium are out of balance in your body. A quick drop in sodium levels can cause weakness, headache, nausea, and muscle cramps.

Read more »



Hypercalcemia is a condition in which you have too much calcium in your blood. Serious cases could cause symptoms like abdominal pain, nausea, constipation, and weakness.

Read more »


Iron Deficiency Anemia

Iron-deficiency anemia is the most common type of anemia, which occurs when the body does not have enough of the mineral iron. The body needs iron to produce hemoglobin.

Read more »


Postpartum Depression

Postpartum depression affects as many as 13 percent of new mothers. In the U.S., that's half a million women. Learn about symptoms, causes, risks, and more.

Read more »


Congestive Heart Failure (CHF)

Congestive heart failure (CHF) is a chronic condition that affects the chambers of your heart. CHF refers to fluid buildup around your heart.

Read more »


Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

Read more »


Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an immune reaction to gluten. Symptoms vary but can include arthritis, fatigue, and abdominal symptoms.

Read more »


Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

Read more »


Migraine with Aura

Migraine is a disorder characterized by repeated attacks of severe headache. Symptoms include throbbing or pulsating pain, usually on only one side of the head, and can last between four hours and three days.

Read more »


Alcohol Withdrawal Syndrome

This condition is considered a medical emergency. Urgent care may be required.

Alcohol withdrawal syndrome (AWS) is the name for the symptoms that occur when a heavy drinker suddenly stops or significantly reduces their alcohol intake. With AWS, you may feel mild anxiety and fatigue. You may als...

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.