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What causes general weakness and irritable mood? 30 possible conditions

See a list of possible causes in order from the most common to the least.


Low Blood Sugar (Hypoglycemia)

This condition is considered a medical emergency. Urgent care may be required.

Also known as hypoglycemia, low blood sugar can be a dangerous condition. Hypoglycemia is rare in people who are not suffering from diabetes, the chronic disease that affects the body's ability to regulate blood sugar...

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There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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CFS (Chronic Fatigue Syndrome)

Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by extreme tiredness that can't be explained by an underlying medical condition.

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Sleeplessness, or insomnia, is a serious sleep disorder. It can mean the inability to fall asleep or stay asleep throughout the night, or the tendency to wake too early before having gotten enough sleep.

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Generalized Anxiety Disorder

People who suffer from generalized anxiety disorder, or GAD, worry uncontrollably about common occurrences and situations. The condition may also be called chronic anxiety neurosis.GAD is different than normal feeling...

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Diabetes Overview

Diabetes is a group of chronic metabolic diseases caused by defects in insulin production or function. Advanced diabetes may cause stomach pain, nausea, dizziness, and cramps.

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Nutritional Deficiencies (Malnutrition)

A nutritional deficiency occurs when the body doesn't absorb the necessary amount of a nutrient. Deficiencies can lead to a variety of health problems.

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Iron Deficiency Anemia

Iron-deficiency anemia is the most common type of anemia, which occurs when the body does not have enough of the mineral iron. The body needs iron to produce hemoglobin.

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PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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This condition is considered a medical emergency. Urgent care may be required.

Meningococcemia is a bacterial blood infection caused by the same type of bacteria that causes some types of meningitis. Advanced symptoms of the infection include blood clots and bleeding under the skin.

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Postpartum Depression

Postpartum depression affects as many as 13 percent of new mothers. In the U.S., that's half a million women. Learn about symptoms, causes, risks, and more.

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Sinus Infections (Sinusitis)

A sinus infection causes the sinuses and nasal passages to become inflamed. Facial swelling is a common sign of this type of infection.

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Bipolar Disorder

Bipolar disorder mental illness marked by extreme from mania to depression. Bipolar disorder is also called bipolar disease or manic depression.

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Type 1 Diabetes

Type 1 diabetes is a chronic disease that result high levels of glucose in the blood due to a lack of insulin production. Glucose is a natural sugar that your body uses as a source of energy.

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Dementia Overview

Dementia may affect memory, thinking, language, judgment, and behavior. Mental impairment must affect at least two brain functions to be considered dementia.

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This condition is considered a medical emergency. Urgent care may be required.

A concussion is a mild traumatic brain injury. Usually it occurs after an impact to your head or after a whiplash-type injury. A concussion can cause many severe symptoms that affect brain function.

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Cocaine and related disorders

Cocaine is extracted from the coca plant, which grows in Central and South America. It is processed into many forms for use as an illegal drug of abuse.

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Whiplash occurs when a person's head moves backward and then forward very suddenly with great force. This injury is most common following a car collision.

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Migraine with Aura

Migraine is a disorder characterized by repeated attacks of severe headache. Symptoms include throbbing or pulsating pain, usually on only one side of the head, and can last between four hours and three days.

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This condition is considered a medical emergency. Urgent care may be required.

Encephalitis is an inflammation of the brain tissue. It's most often caused by viral infections. In some cases, bacterial infections can cause encephalitis.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.