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What causes gastrointestinal bleeding and pain? 32 possible conditions

See a list of possible causes in order from the most common to the least.



Hemorrhoids, also called piles, are swollen veins located around the anus or in the lower rectum. Internal hemorrhoids develop within the anus; external hemorrhoids develop outside of the anus. Of the two forms...

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Crohn’s Disease

Crohn's disease is a chronic bowel disease that causes severe inflammation of the digestive tract. It is associated with abdominal pain, diarrhea, and may affect your quality of life. Crohn's disease is characterized b...

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Stomach Ulcer

Stomach ulcers are painful sores in the stomach lining or small intestine. They occur when the mucus that protects the stomach from digestive juices is reduced.

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Peptic Ulcer

Peptic ulcers are painful sores in the lining of the stomach, esophagus, or small intestine. Peptic ulcers are a fairly common health problem.

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Cirrhosis is the severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections.

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Types of Acid Reflux

Acid reflux symptoms are caused when stomach contents flow up from the stomach back into the esophagus, causing symptoms like heartburn, stomach pain, and burping.

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This condition is considered a medical emergency. Urgent care may be required.

Most common in boys, intussusception occurs when a portion of the intestines become enfolded, causing a blockage. Symptoms include abdominal pain, vomiting, bloody stools, and others. It is potentially life-threatening.

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Colorectal (Colon) Cancer

Colorectal cancer is a cancer that originates in the rectum or colon. Both of these organs are located at the lower portion of your digestive system. The colon is at the end of the large intestine and the rectum is a...

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Diverticula are bulging sacs that can appear in the lining of your large intestine. Diverticulitis occurs when these sacs get acutely infected or inflamed.

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Alcoholic Liver Disease

Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage o...

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The number one symptom of shigellosis, a bacterial infection, is diarrhea. Its symptoms vary in intensity, so you can have this infection and not know it.

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Stomach Cancer (Gastric Adenocarcinoma)

Stomach cancer occurs when cancerous cells form in the stomach lining. Because it's difficult to detect, it's often not diagnosed until it's more advanced.

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Ulcerative Colitis

Ulcerative colitis is an inflammatory bowel disease. It occurs when the lining of the large intestine (colon or bowel) and the rectum become inflamed.

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Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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Anal Cancer

Anal cancer is an uncommon cancer in the anal canal. It's easy to mistake symptoms of anal cancer for other conditions such as hemorrhoids, which could delay a diagnosis. Human papillomavirus is closely related to ana...

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Hemophilia A

Hemophilia A (factor VIII deficiency) is the most common form of the blood clotting disorder hemophilia. It can cause prolonged bleeding, tight joints, and unexplained bruising.

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The Many Sides of Bacterial Gastroenteritis

Bacterial infections are common causes of gastrointestinal infections. This type of infection is also called "food poisoning" and is often caused by poor hygiene or ingesting foods contaminated with bacteria.

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Colitis is inflammation of the colon, often causing discomfort and pain in the abdomen, as well as other gastrointestinal symptoms. Colitis has many possible causes, which determine the type.

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Polymyalgia Rheumatica

Polymyalgia rheumatica is an inflammatory disorder that causes pain and stiffness in various parts of the body, including the shoulders, neck, arms, thighs, and hips. The cause of this disorder is unknown.

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Proctitis is a condition in which when the lining tissue of the inner rectum becomes inflamed. The rectum is part of your lower digestive system.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.