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What causes gastrointestinal bleeding and loss of appetite? 15 possible conditions

See a list of possible causes in order from the most common to the least.



Weakness in your stomach lining allows digestive juices to damage and inflame it, causing gastritis. It comes in both acute and chronic forms.

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Types of Acid Reflux

Acid reflux symptoms are caused when stomach contents flow up from the stomach back into the esophagus, causing symptoms like heartburn, stomach pain, and burping.

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Alcoholic Liver Disease

Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage o...

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Peptic Ulcer

Peptic ulcers are painful sores in the lining of the stomach, esophagus, or small intestine. Peptic ulcers are a fairly common health problem.

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Cirrhosis is the severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections.

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Crohn’s Disease

Crohn's disease is a chronic bowel disease that causes severe inflammation of the digestive tract. It is associated with abdominal pain, diarrhea, and may affect your quality of life. Crohn's disease is characterized b...

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Stomach Cancer (Gastric Adenocarcinoma)

Stomach cancer occurs when cancerous cells form in the stomach lining. Because it's difficult to detect, it's often not diagnosed until it's more advanced.

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Ulcerative Colitis

Ulcerative colitis is an inflammatory bowel disease. It occurs when the lining of the large intestine (colon or bowel) and the rectum become inflamed.

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Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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The Many Sides of Bacterial Gastroenteritis

Bacterial infections are common causes of gastrointestinal infections. This type of infection is also called "food poisoning" and is often caused by poor hygiene or ingesting foods contaminated with bacteria.

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Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an immune reaction to gluten. Symptoms vary but can include arthritis, fatigue, and abdominal symptoms.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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E. coli Infection

E. coli is a type of bacteria normally found in intestines. But certain kinds of E. coli can cause infection and severe symptoms like diarrhea and dehydration.

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Yellow fever

Yellow fever is a serious, potentially deadly flu-like disease spread by mosquitoes. It's found mostly in Africa and South America. Symptoms of stage 3 yellow fever include abdominal pain, vomiting, and jaundice.

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This condition is considered a medical emergency. Urgent care may be required.

Anthrax is a serious illness caused by a microbe that lives in soil, called Bacillus anthracis. Inhalation may result in cold and flu symptoms; signs of ingestion include nausea and abdominal pain.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.