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What causes fever, loss of appetite and unintentional weight loss? 24 possible conditions

See a list of possible causes in order from the most common to the least.



Hepatitis refers to an inflammatory condition of the liver. It's commonly caused by a viral infection, but there are other possible causes of hepatitis.

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Lung Cancer Overview

Lung cancer is a cancer that originates in the lungs. Lung cancer often goes undetected in the early stages, since symptoms don't usually present themselves until the advanced stages of the disease.

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Viral Gastroenteritis

Viral gastroenteritis, also known as the stomach flu, is caused by a number of different viruses. Its symptoms usually last for two to three days.

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Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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Crohn’s Disease

Crohn's disease is a chronic bowel disease that causes severe inflammation of the digestive tract. It is associated with abdominal pain, diarrhea, and may affect your quality of life. Crohn's disease is characterized b...

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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Acute HIV Infection

Acute HIV infection is the primary stage of infection by the human immunodeficiency virus. There are several telltale symptoms, one of which is a rash.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common kind of lung cancer, comprising 85 to 90 percent of lung cancer diagnoses. It does not grow as quickly as the other type of lung cancer, small cell lung cancer.

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Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease and the most common type of lupus. One of its common symptoms is a rash on the cheeks and nose called a "butterfly rash."

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Hodgkin's Disease

Hodgkin's disease is a type of lymphoma, a blood cancer that starts in the lymphatic system. It can occur at any age, but is most prevalent between the ages of 15 and 40 and after the age of 55.

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Endocarditis is inflammation of the inner lining of the heart. Possible symptoms of this condition include pale skin, chills, and night sweats.

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Chlamydia Infection

Chlamydia is a sexually transmitted disease that should be treated quickly in order to avoid complications. It is caused by bacteria that are usually spread through sexual contact. People with chlamydia often don't hav...

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Brucellosis is a rare disease usually spread through ingesting infected raw meat and unpasteurized milk. Back pain, lethargy, chills, and fever may occur and could lead to complications.

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Leishmaniasis is a parasitic disease caused by the Leishmania parasite found in sand flies.

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Ankylosing Spondylitis

Ankylosing spondylitis is a form of arthritis that primarily affects your spine. It causes severe inflammation of the vertebrae that might eventually lead to chronic pain and disability.

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Temporal Arteritis

Temporal arteritis is a condition in which the temporal arteries, which supply blood to the head and scalp, become inflamed or damaged. Scalp sensitivity or tenderness is a symptom.

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Valley Fever (Coccidioidomycosis)

Coccidioidomycosis, also known as valley fever, is a fungal infection that starts in the lungs and can potentially spread to the rest of the body. Fever, chills and sweating are common.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.