What causes fatigue? 251 possible conditions

See a list of possible causes in order from the most common to the least.


Cardiogenic Shock

This condition is considered a medical emergency. Urgent care may be required.

Cardiogenic shock is a rare condition in which the heart is so damaged that it is unable to supply sufficient blood to bodily organs. Sweating and cold extremities are potential signs of this condition.

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Generalized Anxiety Disorder

People who suffer from generalized anxiety disorder, or GAD, worry uncontrollably about common occurrences and situations. The condition may also be called chronic anxiety neurosis.GAD is different than normal feeling...

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Tension Headaches

A tension headache is the most common type of headache. This type of headache can cause mild or moderate pain in the head, neck, and behind the eyes. Some patients say that a tension headache feels like a tight ban...

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Dysthymia is chronic depression with recurring symptoms of sadness and hopelessness lasting for several years. It is not characterized by acute depressive episodes but by an ongoing depressed feeling. Dysthymia is mos...

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Underactive Pituitary Gland (Hypopituitarism)

The pituitary gland releases hormones that play roles in body processes like bone growth and metabolism. An underactive pituitary can disrupt these processes. Causes may include tumors, traumatic injuries, and diseases.

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Colorectal (Colon) Cancer

Colorectal cancer is a cancer that originates in the rectum or colon. Both of these organs are located at the lower portion of your digestive system. The colon is at the end of the large intestine and the rectum is a...

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Chronic Kidney Disease

Chronic kidney disease is a progressive, irreversible destruction of the kidneys. The most common causes are high blood pressure and diabetes. Symptoms don't show until about 90 percent of the kidney has been destroyed.

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Liver Cancer

Liver cancer causes destruction of liver cells and interferes with the ability of the liver to function normally. Cancer that originates in the liver can spread from the liver to other parts of the body.

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Leukemia is a cancer of the blood cells. Excessive sweating at night, constant fatigue, weight loss, bone pain, and easy bleeding or bruising are all signs of this disease.

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Pyelonephritis is an inflammation of the kidney and upper urinary tract. Symptoms include flushed skin, back pain, fever, and nausea.

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Hepatitis is swelling and inflammation of the liver. It's usually caused by a viral infection. There are several types of hepatitis, including: A, B, C, D, and E. Symptoms may not occur until liver damage occurs.

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Mitral Valve Prolapse

Your mitral valve is located on the left side of your heart, between two chambers, the atrium and the ventricle. Blood is pumped from the left atrium through the mitral valve and into the left ventricle on its way t...

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Pneumothorax (Collapsed Lung)

Pneumothorax is a collapsed lung. This occurs when air becomes trapped in the space around the lungs. Along with a steady ache in the chest and shortness of breath, your skin or lips may turn blue.

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This condition is considered a medical emergency. Urgent care may be required.

A concussion is a mild traumatic brain injury. Usually it occurs after an impact to your head or after a whiplash-type injury. A concussion can cause many severe symptoms that affect brain function.

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Atherosclerosis is a narrowing of the arteries caused by a buildup of plaque. Common symptoms include chest pain, muscle weakness, and more. If not treated, it can lead to heart attack, stroke, and heart failure.

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Ischemic Cardiomyopathy

Ischemic cardiomyopathy is a condition that occurs when the heart muscle is weakened due to insufficient blood flow to the heart's muscle. This inhibits the heart's ability to pump blood and can lead to heart failure.

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Cirrhosis is severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections. Certain medications and disorder can also cause cirrhosis.

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Sickle Cell Anemia

Sickle cell anemia is a genetic disease that causes red blood cells to have an abnormal shape, causing blood flow problems. This can lead to tissue damage and pain, as well as enlarged spleen, anemia, and other symptoms.

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Thalassemia is an inherited blood disorder that results in excessive destruction of red blood cells (anemia). Symptoms depend on its severity, and can range from minor anemia to enlargement of organs or fetal death.

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Multiple Sclerosis Overview

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. MS can cause varying symptoms that appear with a wide range of severity, from mild discomfort to complete disability.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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