Fatigue, Weight loss: 66 Possible Causes
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What causes fatigue and weight loss? 66 possible conditions

See a list of possible causes in order from the most common to the least.


Anorexia Nervosa

Anorexia nervosa is an eating disorder that can result in severe weight loss. Learn more about warning signs and treatment.

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There are many symptoms of HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Learn more about anxiety with this overview of anxiety disorders.

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Diabetes Overview

Diabetes is a group of chronic metabolic diseases caused by defects in insulin production or function. Advanced diabetes may cause stomach pain, nausea, dizziness, and cramps.

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. Read more on whom it affects and how to treat it.

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Hepatitis refers to an inflammatory condition of the liver. It's commonly caused by a viral infection, but there are other possible causes of hepatitis.

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Heart Failure

Heart failure is characterized by the heart's inability to pump an adequate supply of blood. Learn about heart failure symptoms, causes, types, and treatment.

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The thyroid gland produces a hormone that controls how your cells use energy. Hyperthyroidism occurs when the body produces excessive amounts.

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Peptic Ulcer

Peptic ulcers are painful sores in the lining of the stomach, esophagus, or small intestine. Peptic ulcers are a fairly common health problem.

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Cirrhosis is the severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections.

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Bipolar Disorder

Bipolar disorder is a mental illness marked by extreme shifts in mood ranging from mania to depression. It is also called bipolar disease or manic depression.

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Type 1 Diabetes

Type 1 diabetes is a chronic disease that result high levels of glucose in the blood due to a lack of insulin production. Glucose is a natural sugar that your body uses as a source of energy.

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Underactive Pituitary Gland (Hypopituitarism)

Hypopituitarism occurs when your pituitary gland in your brain is not releasing one or more of the eight hormones it should be releasing.

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Hodgkin's Disease

Learn more about a type of blood cancer called Hodgkin's disease (HD), including its symptoms, causes, diagnosis, and treatments.

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Leukemia is a cancer of the blood cells. There are several types of blood cells, including red blood cells (RBCs), white blood cells (WBCs), and platelets. Generally, leukemia refers to cancers of the WBCs. Two types o...

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. Read more about the symptoms of this infection and treatment options.

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Lactose Intolerance

Lactose intolerance is the inability to break down a type of natural sugar called lactose. Lactose is commonly found in dairy products, such as milk and yogurt. A person becomes lactose intolerant when his or her smal...

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Smoking is the leading cause of emphysema, a disease of the lungs that makes it hard to breathe. Learn more about how emphysema affects you and how it's treated.

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Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an abnormal immune reaction to gluten. Learn about celiac disease systems, diagnosis, and treatment.

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Postpartum Depression

Postpartum depression affects as many as 13 percent of new mothers. In the U.S., that's half a million women. Learn about symptoms, causes, risks, and more.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.