Let's see if we can figure out what's causing your symptoms.
Select additional symptoms and we'll narrow your results.

What causes fatigue and painful urination? 10 possible conditions

See a list of possible causes in order from the most common to the least.


Urinary Tract Infection

UTIs are usually caused by bacteria and can occur in any part of the urinary tract. Symptoms of upper UTIs include pain in the upper back, chills, fever, and nausea.

Read more »


Bladder Infection

A bladder infection is a bacterial infection. It also may be called a urinary tract infection (UTI), which refers to infection anywhere in the urinary tract, including the bladder, kidneys, ureters, or urethra.

Read more »


Pelvic Inflammatory Disease (PID)

Pelvic inflammatory disease (PID) is an infection of the reproductive organs in women. It's marked by pain in the abdomen, especially during urination or sex.

Read more »


Bladder Cancer

Bladder cancer occurs in the tissues of the bladder, which is the organ that holds urine. Fatigue, weight loss, painful or frequent urination, and abdominal or back pain are symptoms.

Read more »


Renal Cell Cancer

Renal cell carcinoma is the most common kind of kidney cancer found in adults. Often aggressive, it occurs when cancer cells grow uncontrollably in the lining of the tubules of the kidney, causing many possible symptoms.

Read more »



Pyelonephritis is an inflammation of the kidney and upper urinary tract. Symptoms include flushed skin, back pain, fever, and nausea.

Read more »


Chlamydia Infection

Chlamydia is a sexually transmitted disease that should be treated quickly in order to avoid complications. It is caused by bacteria that are usually spread through sexual contact. People with chlamydia often don't hav...

Read more »


Transitional Cell Cancer (Malignant Neoplasm of Ureter)

Urine collects in the renal pelvis and is drained by the ureter into the bladder. When cancer develops in the renal pelvis or ureter, it begins in transitional cells, which line these organs.

Read more »


Genital Herpes

Genital herpes is a sexually transmitted infection (STI). This STD causes herpes sores, which are painful blisters (fluid-filled bumps) that can break open and ooze fluid. According to the Centers for Disease Contro...

Read more »



Hydronephrosis is a condition that typically occurs when one kidney becomes swollen due to the failure of normal drainage of urine from the kidney to the bladder. This swelling most commonly affects only one kidney, bu...

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.