Let's see if we can figure out what's causing your symptoms.
Select additional symptoms and we'll narrow your results.

What causes fatigue, pain and rash? 21 possible conditions

See a list of possible causes in order from the most common to the least.



Cellulitis is a common, often painful skin infection that first appears as a red, swollen area that feels hot and tender to the touch. If left untreated, it can become life-threatening.

Read more »


Chemical Burns

This condition is considered a medical emergency. Urgent care may be required.

Chemical burns occur when the skin or eyes come into contact with irritants, such as acids or bases. Symptoms vary, but skin reactions, pain or numbness are common.

Read more »


Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease and the most common type of lupus. One of its common symptoms is a rash on the cheeks and nose called a "butterfly rash."

Read more »


Fifth Disease

Fifth disease is caused by a virus and mostly affects children. The disease is marked by feeling unwell, often followed by a red rash on the cheeks.

Read more »


Rheumatic Fever

Rheumatic fever is a possible and potentially serious complication of strep throat. It tends to occur in children between five and 15 years old. Rash is one possible sign of this condition.

Read more »


Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

Read more »


Lyme Disease

Lyme disease is an infectious condition transmitted via tick bite. A "bull's eye" rash at the site of the bite is an early symptom of this disease.

Read more »



Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

Read more »


Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease is a rare, often fatal illness. One of its late-stage symptoms is a bleeding rash over the entire body.

Read more »



Poliomyelitis, or polio, is a highly contagious disease that is caused by a virus that attacks the body's nervous system. It is most likely to be contracted by children under five years old.

Read more »



Erysipelas is a bacterial infection in the upper layer of your skin. A raised rash or blisters occur most commonly on the legs and face, and may be accompanied by fever and chills.

Read more »


Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

Read more »


West Nile Virus Infection (West Nile Fever)

Spread by mosquitos, West Nile virus symptoms can vary in severity. Diarrhea and abdominal pain usually appears within two weeks of infection.

Read more »



Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

Read more »


Acute HIV Infection

Acute HIV infection is the primary stage of infection by the human immunodeficiency virus. There are several telltale symptoms, one of which is a rash.

Read more »


The War of Cells: Graft vs. Host Disease

Graft vs. Host Disease is a common reaction that develops after an allogeneic bone marrow transplant. It usually goes away after the transplant has become established. It causes symptoms throughout the body's systems.

Read more »



Trichinosis is a roundworm that can infect humans when they eat certain undercooked meats. Rashes are a possible symptom of trichinosis after the larvae enter the muscle tissue.

Read more »


Dengue Fever

Dengue fever is a disease that affects much of the tropical region and is caused by one of four dengue viruses. A skin rash between two and five days after the initial fever is a common symptom.

Read more »


Colorado Tick Fever

An infected Rocky Mountain Wood tick can spread Colorado tick fever, a viral infection. A faint, occasional rash is one symptom of this condition.

Read more »


MRSA (Staph) Infection

MRSA (methicillin-resistant Staphylococcus) is a type of contagious bacterial infection that is resistant to beta-lactam antibiotics. CA-MRSA typically causes lesions that are red, swollen, and painful to touch.

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.