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What causes fatigue, night sweats and unintentional weight loss? 14 possible conditions

See a list of possible causes in order from the most common to the least.



Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Colitis is inflammation of the colon, often causing discomfort and pain in the abdomen, as well as other gastrointestinal symptoms. Colitis has many possible causes, which determine the type.

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Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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Non-Hodgkin’s Lymphoma

Non-Hodgkin's lymphoma is a lymphatic system cancer. Symptoms may include swollen lymph nodes, chest pain, fatigue, and fever.

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Hodgkin's Disease

Hodgkin's disease is a type of lymphoma, a blood cancer that starts in the lymphatic system. It can occur at any age, but is most prevalent between the ages of 15 and 40 and after the age of 55.

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Acute Lymphocytic Leukemia

Acute lymphocytic leukemia (ALL) is the most common cancer in childhood, although it can also occur in adults. ALL is a cancer of the blood and bone marrow. Cancer occurs when abnormal cells in a part of the body begi...

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Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a cancer that occurs in the blood and the marrow of the bones. Marrow is sponge-like material inside the bones that produces blood cells. AML specifically affects the white blood cells o...

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Chronic Myelogenous Leukemia (CML)

Leukemia is a type of cancer that starts in the blood or blood-forming tissues. There are many different types of leukemia, and treatment is different for each one. Chronic leukemias are slower growing than acut...

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Chronic Lymphocytic Leukemia

Leukemia is a type of cancer that affects the blood and blood-forming tissues. There are many types of leukemia, each affecting different kinds of blood cells. Chronic lymphocytic leukemia, or CLL, is a cancer of th...

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Infective Endocarditis

Infective endocarditis is an infection of the heart, normally caused by bacteria in the blood stream. It is a serious medical condition. If left untreated, the infection can damage your heart and may even cause death.

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Endocarditis is inflammation of the inner lining of the heart. Possible symptoms of this condition include pale skin, chills, and night sweats.

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Leishmaniasis is a parasitic disease caused by the Leishmania parasite found in sand flies.

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Burkitt's Lymphoma

Burkitt's lymphoma is a relatively rare and aggressive form of non-Hodgkin's lymphoma, a type of cancer of the lymphatic system. It's most common in children living in sub-Saharan Africa.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.