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What causes fatigue and muscle twitch? 6 possible conditions

See a list of possible causes in order from the most common to the least.


Peripheral Neuropathy

Peripheral neuropathy occurs when nerves malfunction because they're damaged or destroyed. You'll notice a tingling, numbness, or weakness, and possibly sweating, constipation, or diarrhea.

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Hypercalcemia is a condition in which you have too much calcium in your blood. Serious cases could cause symptoms like abdominal pain, nausea, constipation, and weakness.

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Medullary Cystic Disease

Medullary cystic kidney disease is a rare condition that causes cysts to form on kidneys. Kidney failure may result, symptoms of which can include changes in skin color and itchy skin.

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Chronic Kidney Disease

Chronic kidney disease (CKD) is the progressive and irreversible destruction of the kidneys. The most common causes of CKD are high blood pressure and diabetes.

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End-Stage Kidney Disease

In end-stage kidney disease, also known as end-stage renal disease (ESRD), the kidneys are functioning below 10 percent of their normal function.

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Glomerulonephritis is a serious illness that can be life-threatening and requires immediate treatment. The condition is sometimes called nephritis.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.