Fatigue, Loss of appetite, Swollen ankle: 10 Possible Causes
Let's see if we can figure out what's causing your symptoms.
Select additional symptoms and we'll narrow your results.

What causes fatigue, loss of appetite and swollen ankle? 10 possible conditions

See a list of possible causes in order from the most common to the least.



The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause complications like obesity and heart disease.

Read more »



Bleeding or spotting, increased need to urinate, tender breasts, fatigue, nausea, and missed period are signs of pregnancy.

Read more »


Congestive Heart Failure (CHF)

Congestive heart failure (CHF) is a chronic condition that affects the chambers of your heart. CHF refers to fluid buildup around your heart.

Read more »


PMS (Premenstrual Syndrome)

Premenstrual syndrome causes a wide variety of emotional and physical symptoms. Learn more about it.

Read more »



Cirrhosis is the severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections.

Read more »


Heart Failure

Heart failure is characterized by the heart's inability to pump an adequate supply of blood. Learn about heart failure symptoms, causes, types, and treatment.

Read more »


Chronic Kidney Disease

Chronic kidney disease (CKD) is the progressive and irreversible destruction of the kidneys. The most common causes of CKD are high blood pressure and diabetes.

Read more »


Ischemic Cardiomyopathy

Ischemic cardiomyopathy (IC) is a condition that occurs when the heart muscle is weakened. It's usually caused by heart attack or coronary artery disease.

Read more »



Endocarditis, also known as infective endocarditis, is a condition in which your heart's inner lining is inflamed. Learn about causes and symptoms.

Read more »


Teenage Pregnancy

Teenage pregnancy is pregnancy in a woman 19 years of age or younger. A woman can get pregnant if she has vaginal sex with a man at any age after she has started having regular monthly periods. Some signs of pregnanc...

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.