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Leg pain

What causes fatigue and leg pain? 6 possible conditions

See a list of possible causes in order from the most common to the least.



Radiculopathy refers to disease of the spinal nerve roots. Radiculopathy produces pain , numbness, or weakness radiating from the spine.

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Multiple Sclerosis Overview

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. MS can cause varying symptoms that appear with a wide range of severity, from mild discomfort to complete disability.

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Atherosclerosis is a narrowing of the arteries caused by a buildup of plaque. It's also called arteriosclerosis or hardening of the arteries.

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Poliomyelitis, or polio, is a highly contagious disease that is caused by a virus that attacks the body's nervous system. It is most likely to be contracted by children under five years old.

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Necrotizing Vasculitis

This condition is considered a medical emergency. Urgent care may be required.

Necrotizing vasculitis is the inflammation of blood vessel walls. It can interrupt blood flow, causing skin, muscle, and blood vessel damage.

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Venous insufficiency

Venous insufficiency is a condition where the flow of blood through the veins is blocked, causing blood to pool in the legs. It's often caused by blood clots.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.