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What causes fatigue, headache and swollen ankle? 5 possible conditions

See a list of possible causes in order from the most common to the least.



The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause complications like obesity and heart disease.

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PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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Glomerulonephritis is a serious illness that can be life-threatening and requires immediate treatment. The condition is sometimes called nephritis.

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Chronic Kidney Disease

Chronic kidney disease (CKD) is the progressive and irreversible destruction of the kidneys. The most common causes of CKD are high blood pressure and diabetes.

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Chronic Bronchitis

People often develop acute bronchitis after a viral chest infection. Blue-colored lips ankle or foot swelling can result.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.