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What causes fatigue, headache and rash? 17 possible conditions

See a list of possible causes in order from the most common to the least.

1

Systemic Lupus Erythematosus

Systemic lupus erythematosus, the most common form of lupus, is a chronic autoimmune disease that can cause severe fatigue and joint pain. Learn more about it.

Read more »

2

Infectious Mononucleosis

Infectious mononucleosis, or mono, refers to a group of symptoms usually caused by the Epstein-Barr virus (EBV).

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3

MRSA (Staph) Infection

MRSA is an infection caused by a type of staph bacteria that's resistant to many different antibiotics. Learn about its symptoms, causes, and treatment.

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4

Fifth Disease

Fifth disease is common in children. It causes a red rash on the arms, legs, and cheeks, and a virus called parvovirus B19 causes it.

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5

Chemical Burns

This condition is considered a medical emergency. Urgent care may be required.

Find information about chemical burns and how to prevent them. Learn about the causes, symptoms, and treatment of chemical burns.

Read more »

6

Lyme Disease

Lyme disease is an infectious disease that's transmitted to humans through tick bites. Learn how Lyme disease is diagnosed and treated, and learn how to prevent tick bites.

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7

Leukemia

Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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8

Addisonian Crisis (Acute Adrenal Crisis)

This condition is considered a medical emergency. Urgent care may be required.

An Addisonian crisis occurs when levels of cortisol suddenly drop. Learn more about an Addisonian crisis, including symptoms, risk factors, and treatment.

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9

Syphilis

Syphilis is a sexually transmitted infection. It is caused by a type of bacteria known as Treponema pallidum. According to the Centers for Disease Control and Prevention, in 2006, more than 36,000 cases of syphilis wer...

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10

West Nile Virus Infection (West Nile Fever)

Learn about the causes and symptoms of the West Nile virus.

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11

Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease is a rare, often fatal illness. One of its late-stage symptoms is a bleeding rash over the entire body.

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12

Sarcoidosis

Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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13

Acute HIV Infection

Acute HIV infection occurs soon after someone is infected with HIV. Learn about its symptoms, diagnosis, treatment, and prevention.

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14

Polio

Poliomyelitis, or polio, is a highly contagious disease that is caused by a virus that attacks the body's nervous system.

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15

Dengue Fever

Dengue fever is a disease that affects much of the tropical region and is caused by one of four dengue viruses. A skin rash between two and five days after the initial fever is a common symptom.

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16

Colorado Tick Fever

Colorado tick fever is a viral infection transmitted through a bite from an infected tick. Learn about Colorado tick fever symptoms, diagnosis, and treatment.

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17

Transfusion Reactions

A transfusion reaction is when your body has an adverse response to a blood transfusion. Learn how transfusion reactions occur and how to minimize your risk.

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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