Splenomegaly: Causes & Finding Relief
Let's see if we can figure out what's causing your enlarged spleen.
Select additional symptoms and we'll narrow your results.

What causes enlarged spleen? 18 possible conditions

Splenomegaly is a condition that occurs when your spleen becomes enlarged. It is also commonly referred to as enlarged spleen or spleen enlargement. The spleen is a part of your lymphatic system. The spleen helps the immune system by storing white blood... Read more

See a list of possible causes in order from the most common to the least.

1

Chronic Myelogenous Leukemia (CML)

Leukemia is a type of cancer that starts in the blood or blood-forming tissues. There are many different types of leukemia, and treatment is different for each one. Chronic leukemias are slower growing than acut...

Read more »

2

Idiopathic Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) is a group of blood disorders that occur when red blood cells are destroyed faster than they're produced. Symptoms include weakness, shortness of breath, rapid heart rate, and others.

Read more »

3

Hodgkin's Disease

Learn more about a type of blood cancer called Hodgkin's disease (HD), including its symptoms, causes, diagnosis, and treatments.

Read more »

4

Malaria

Malaria is a life-threatening disease. It's typically transmitted through the bite of an infected Anopheles mosquito.

Read more »

5

Hemolytic Anemia

When dying red blood cells outpace the bone marrow's production in a person, hemolytic anemia occurs. Hemolytic anemia can be extrinsic or intrinsic.

Read more »

6

Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AHA) is a group of conditions where a person's immune system destroys their red blood cells (RBCs). These rare conditions occur when antibodies-proteins that normally protect us from viruse...

Read more »

7

Familial Combined Hyperlipidemia

Familial combined hyperlipidemia is an inherited disorder that causes high cholesterol and high levels of triglycerides. Some individuals have no physical symptoms from the disease. For others, it may cause chest pain.

Read more »

8

Hyperlipoproteinemia

Hyperlipoproteinemia is a common disorder that results in high levels of lipids circulating in the blood. This can cause pancreatitis, abdominal pain, enlarged liver and other symptoms.

Read more »

9

Chronic Lymphocytic Leukemia

Leukemia is a type of cancer that affects the blood and blood-forming tissues. There are many types of leukemia, each affecting different kinds of blood cells. Chronic lymphocytic leukemia, or CLL, is a cancer of th...

Read more »

10

Juvenile Rheumatoid Arthritis

Juvenile rheumatoid arthritis is a form of chronic arthritis that affects children. It is a long-term autoimmune condition characterized by stiffness and swelling in the joints. Most cases of JRA are mild.

Read more »

11

Infectious Mononucleosis

Infectious mononucleosis, or mono, refers to a group of symptoms usually caused by the Epstein-Barr virus (EBV).

Read more »

12

Adult-Onset Still's Disease

This relatively rare inflammatory condition begins with fever and may lead to arthritis. Women and people between the ages of 16 and 46 are most at risk.

Read more »

13

Leukemia

Leukemia is a cancer of the blood cells. There are several types of blood cells, including red blood cells (RBCs), white blood cells (WBCs), and platelets. Generally, leukemia refers to cancers of the WBCs. Two types o...

Read more »

14

G6PD Deficiency

G6PD deficiency is a genetic condition caused by a lack of the G6PD enzyme in the blood. Learn about G6PD deficiency symptoms, diagnosis, and treatment.

Read more »

15

Hyperlipidemia

Cholesterol is a natural substance, but too much of it can clog blood vessels and lead to heart attack or stroke. High cholesterol levels can also cause yellow deposits in the eyes or in tendons.

Read more »

16

Acrodermatitis and Your Child

Acrodermatitis is a skin condition that typically affects children between the ages of 6 months and 12 years. The condition causes fever, fatigue, and itchy red and purple blisters to form on the body.

Read more »

17

Hyperlipoproteinemia Type IV

Hyperlipoproteinemia type IV leads to higher-than-normal triglyceride level due to a genetic defect. This may cause atherosclerosis and increase risk for certain heart conditions, including coronary artery disease.

Read more »

18

Gaucher's Disease

Gaucher disease is an inherited condition in which your body does not store fatty materials (called lipids) correctly. Fatty substances can build up around your vital organs, including your liver, spleen, lungs, bones...

Read more »

This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
Advertisement
Advertisement
Advertisement