What causes depressed mood, general weakness and weight gain? 9 possible conditions

See a list of possible causes in order from the most common to the least.



The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause complications like obesity and heart disease.

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Obesity is defined as having a body mass index (BMI) of 30 or more. BMI is calculated using a person's weight and height. It can lead to other conditions like diabetes, heart disease, and cancer.

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There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Postpartum Depression

Postpartum depression affects as many as 13 percent of new mothers. In the U.S., that's half a million women. Learn about symptoms, causes, risks, and more.

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Seasonal Affective Disorder

Seasonal affective disorder (SAD) is a form of depression. People affected by SAD display symptoms of depression at the same time every year, typically during the fall and winter months. According to the America...

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Bipolar Disorder

Bipolar disorder mental illness marked by extreme from mania to depression. Bipolar disorder is also called bipolar disease or manic depression.

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PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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Primary Hypothyroidism

Your thyroid gland controls the metabolism of all your cells. Your pituitary gland releases a hormone known as TSH (thyroid stimulating hormone) to stimulate your thyroid. Your thyroid then releases two hormones, T3 an...

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Hashimoto's Disease

Hashimoto's disease is a condition that damages the thyroid's ability to function properly. It can cause a goiter, or enlarged thyroid, which can make the front of the neck look swollen.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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