What causes dark urine and pain? 30 possible conditions

See a list of possible causes in order from the most common to the least.

1

Gallstones

Gallstones are hard deposits in the gallbladder that can eventually block the exiting bile ducts. Abdominal pain, fever, itchy skin, and jaundice are possible symptoms.

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2

Hepatitis

Hepatitis is swelling and inflammation of the liver. It's usually caused by a viral infection. There are several types of hepatitis, including: A, B, C, D, and E. Symptoms may not occur until liver damage occurs.

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3

Cirrhosis

Cirrhosis is severe scarring and poor function of the liver caused by long-term exposure to toxins such as alcohol or viral infections. Certain medications and disorder can also cause cirrhosis.

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4

Porphyrias

Porphyrias are rare types of genetic blood disorders in which patients have a defect in heme production, an important part of hemoglobin. Blisters are a sign of porphyria cutanea tarda, the most common type of porphyria.

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5

Rhabdomyolysis

Rhabdomyolysis is breakdown of muscle fibers. Muscle breakdown causes the release of myoglobin into the bloodstream. Myoglobin can cause kidney damage. Symptoms include dark urine, muscle weakness, and fatigue. Abou...

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6

Urethral Stricture

The urethra is a tube that helps expel urine from body. When the urethra narrows, it's known as a urethral stricture. Abdominal pain, urge to urinate, and swelling are signs.

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7

Biliary (Bile Duct) Obstruction

A biliary obstruction blocks the bile ducts, which carry bile to the small intestine for digestion and waste removal. An obstruction can be caused by many factors, including gallstones, inflammation, cysts, or tumors.

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8

Chlamydia Infection

Chlamydia is a sexually transmitted disease that should be treated quickly in order to avoid complications. It is caused by bacteria that are usually spread through sexual contact. People with chlamydia often don't hav...

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9

Alcoholic Liver Disease

Damage to the liver from excessive drinking can lead to ALD. Years of alcohol abuse cause the liver to become inflamed and swollen. This damage can also cause scarring known as cirrhosis. Cirrhosis is the final stage o...

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10

Renal Cell Cancer

Renal cell carcinoma is the most common kind of kidney cancer found in adults. Often aggressive, it occurs when cancer cells grow uncontrollably in the lining of the tubules of the kidney, causing many possible symptoms.

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11

G6PD Deficiency

Glucose-6-phosphate dehydrogenase(G6PD) deficiency is a genetic abnormality that leads to an inadequate amount of the necessary enzyme. Without enough G6PD, red blood cells can be destroyed, leading to anemia.

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12

Hepatitis A

Hepatitis A (HAV) is a short-term type of hepatitis. It usually requires no treatment, but symptoms include fever, nausea, jaundice, and itchy skin, among others.

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13

Bladder Stones: The Bad, the Ugly, and the Good

Bladder stones are crystals that form when concentrated urine is left in the bladder after urination, often due to dehydration or being unable to empty the bladder totally. Symptoms include painful urination and others.

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14

Hepatitis C

Hepatitis C is a disease that causes inflammation and infection in the liver. Symptoms of chronic cases may not be obvious at first, whereas acute hepatitis C sets in quickly after exposure to the virus.

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15

Hepatitis B

Hepatitis B is liver inflammation caused by the hepatitis B virus (HBV). It can be chronic or acute, but most cases are chronic. This disease is easily spread through blood, saliva, and other body fluids.

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16

Hepatitis E

The hepatitis E virus is spread most often by contaminated drinking water. It is different from the hep-A virus but the symptoms are similar. Most cases clear up on their own after a few weeks. In other cases, the viru...

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17

Hepatitis D

Hepatitis D is an infection of the hepatitis D virus that causes your liver to swell and is uncommon in the United States. It is almost always contracted by people with hepatitis B.

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18

Acute Pancreatitis

Acute pancreatitis is an inflammation in the pancreas, which causes pain and swelling in the upper left side of the abdomen, nausea, and burping.

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19

Sickle Cell Anemia

Sickle cell anemia is a genetic disease that causes red blood cells to have an abnormal shape, causing blood flow problems. This can lead to tissue damage and pain, as well as enlarged spleen, anemia, and other symptoms.

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20

Transitional Cell Cancer (Malignant Neoplasm of Ureter)

Urine collects in the renal pelvis and is drained by the ureter into the bladder. When cancer develops in the renal pelvis or ureter, it begins in transitional cells, which line these organs.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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