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What causes cough, fatigue and headache? 14 possible conditions

See a list of possible causes in order from the most common to the least.


Common Cold Overview

The common cold is a virus that involves symptoms like sneezing, a runny nose and a headache. Learn the causes, symptoms and treatments for the common cold now!

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Cold and Flu Overview

Common colds and influenza are contagious infections that affect the respiratory system. Both are airborne illnesses, spread through coughing and sneezing. Shared symptoms include headache, cough, sore throat, and more.

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Sinus Infections (Sinusitis)

A sinus infection causes the sinuses and nasal passages to become inflamed. Facial swelling is a common sign of this type of infection.

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Pneumonia is an infection of the lungs. General symptoms include chest pain, fever, cough, nausea, and difficulty breathing. Blue skin, high fever, and bloody mucus are serious signs.

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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MRSA (Staph) Infection

MRSA (methicillin-resistant Staphylococcus) is a type of contagious bacterial infection that is resistant to beta-lactam antibiotics. CA-MRSA typically causes lesions that are red, swollen, and painful to touch.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Chronic Bronchitis

People often develop acute bronchitis after a viral chest infection. Blue-colored lips ankle or foot swelling can result.

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Sarcoidosis is an inflammatory disease that causes granulomas, which are clumps of immune cells, to form in different organs. A skin rash is one symptom of sarcoidosis of the skin.

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Acute Mountain Sickness

Acute mountain sickness (altitude sickness or high altitude pulmonary edema) occurs in high altitudes, especially when exercising. A lack of oxygen can give the skin and lips a blue tinge.

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Absence of Gamma Globulin in Blood

Agammaglobulinemia (AGMX) is an inherited immune system disorder. Passed from parent to child, it is also known as Bruton’s agammaglobulinemia, congenital agammaglobulinemia, and X-linked agammaglobulinemia. AGM...

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Malignant Hypertension (Arteriolar Nephrosclerosis)

This form of high blood pressure comes on very quickly and requires immediate medical help. You're especially at risk if you already have hypertension or smoke.

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Fifth Disease

Fifth disease is caused by a virus and mostly affects children. The disease is marked by feeling unwell, often followed by a red rash on the cheeks.

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Transfusion Reactions

A transfusion reaction is a rare condition that occurs when a person receives a transfusion with blood that is not matched to their blood type. This may cause symptoms such as back pain, fever, fainting, or dizziness.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.