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What causes chills and night sweats? 13 possible conditions

See a list of possible causes in order from the most common to the least.



Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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There are many symptoms of the autoimmune disease HIV/AIDS, including persistent skin rashes, night sweats, and mouth sores.

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Infective Endocarditis

Infective endocarditis is an infection of the heart, normally caused by bacteria in the blood stream. It is a serious medical condition. If left untreated, the infection can damage your heart and may even cause death.

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Hodgkin's Disease

Hodgkin's disease is a type of lymphoma, a blood cancer that starts in the lymphatic system. It can occur at any age, but is most prevalent between the ages of 15 and 40 and after the age of 55.

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Acute Lymphocytic Leukemia

Acute lymphocytic leukemia (ALL) is the most common cancer in childhood, although it can also occur in adults. ALL is a cancer of the blood and bone marrow. Cancer occurs when abnormal cells in a part of the body begi...

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Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a cancer that occurs in the blood and the marrow of the bones. Marrow is sponge-like material inside the bones that produces blood cells. AML specifically affects the white blood cells o...

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Chronic Myelogenous Leukemia (CML)

Leukemia is a type of cancer that starts in the blood or blood-forming tissues. There are many different types of leukemia, and treatment is different for each one. Chronic leukemias are slower growing than acut...

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An empyema is a condition in which pus collects in the pleural space, which is the area between your lungs and the inner surface of your chest wall.

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Chronic Lymphocytic Leukemia

Leukemia is a type of cancer that affects the blood and blood-forming tissues. There are many types of leukemia, each affecting different kinds of blood cells. Chronic lymphocytic leukemia, or CLL, is a cancer of th...

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Valley Fever (Coccidioidomycosis)

Coccidioidomycosis, also known as valley fever, is a fungal infection that starts in the lungs and can potentially spread to the rest of the body. Fever, chills and sweating are common.

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Endocarditis is inflammation of the inner lining of the heart. Possible symptoms of this condition include pale skin, chills, and night sweats.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.