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What causes chest pain and loss of appetite? 22 possible conditions

See a list of possible causes in order from the most common to the least.



Heartburn typically occurs when contents from the stomach back up into the esophagus. This causes a burning sensation in the chest and a bitter taste in the throat or mouth. Heartburn may be prevented by avoiding food...

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Types of Acid Reflux

Acid reflux symptoms are caused when stomach contents flow up from the stomach back into the esophagus, causing symptoms like heartburn, stomach pain, and burping.

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Weakness in your stomach lining allows digestive juices to damage and inflame it, causing gastritis. It comes in both acute and chronic forms.

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Pneumonia is an infection of the lungs caused by fungi, bacteria, or viruses. General symptoms include chest pain, fever, cough, and difficulty breathing.

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Lung Cancer Overview

Lung cancer is a cancer that originates in the lungs. Lung cancer often goes undetected in the early stages, since symptoms don't usually present themselves until the advanced stages of the disease.

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Peptic Ulcer

Peptic ulcers are painful sores in the lining of the stomach, esophagus, or small intestine. Peptic ulcers are a fairly common health problem.

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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Ischemic Cardiomyopathy

Ischemic cardiomyopathy is a condition that occurs when the heart muscle is weakened due to insufficient blood flow to the heart's muscle. This inhibits the heart's ability to pump blood and can lead to heart failure.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common kind of lung cancer, comprising 85 to 90 percent of lung cancer diagnoses. It does not grow as quickly as the other type of lung cancer, small cell lung cancer.

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Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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Ankylosing Spondylitis

Ankylosing spondylitis is a form of arthritis that primarily affects your spine. It causes severe inflammation of the vertebrae that might eventually lead to chronic pain and disability.

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Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease and the most common type of lupus. One of its common symptoms is a rash on the cheeks and nose called a "butterfly rash."

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Dissection of the Aorta

This condition is considered a medical emergency. Urgent care may be required.

The aorta is a large artery that carries blood out of your heart. If you experience a dissection of the aorta, it means that blood has entered the wall of the artery, between the inner and middle layers. This can happe...

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Goodpasture syndrome

Goodpasture syndrome is a rare and potentially life-threatening autoimmune disease. It occurs when the immune system attacks the walls of the lungs and the tiny filtering units in the kidneys. The disorder is name...

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Non-Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Swelling of the face is one potential sign of lung cancer.

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This condition is considered a medical emergency. Urgent care may be required.

Anthrax is a serious illness caused by a microbe that lives in soil, called Bacillus anthracis. Inhalation may result in cold and flu symptoms; signs of ingestion include nausea and abdominal pain.

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Polyarteritis Nodosa

Polyarteritis nodosa (PAN) is a condition that causes swollen arteries. It primarily affects small and medium-sized arteries, which can become inflamed or damaged. This is a serious disease of the blood vessels cause...

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Actinomycosis is a long-term infection that causes abscesses to form in the soft tissues of the body. Lumps in the neck or face can be a sign of actinomycosis.

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Esophageal Cancer

Esophageal cancer occurs when a malignant (cancerous) tumor forms in the lining of the esophagus, which is the muscular tube responsible for moving food from the throat to the stomach. As the cancer grows, it can affec...

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.