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What causes burning sensation and fatigue? 8 possible conditions

See a list of possible causes in order from the most common to the least.



Radiculopathy refers to disease of the spinal nerve roots. Radiculopathy produces pain , numbness, or weakness radiating from the spine.

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Peripheral Neuropathy

Peripheral neuropathy occurs when nerves malfunction because they're damaged or destroyed. You'll notice a tingling, numbness, or weakness, and possibly sweating, constipation, or diarrhea.

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Mononeuropathy is a pathological effect of a single large nerve. It can be caused by injury, nutritional deficiency, or autoimmune condition. Common symptoms are numbness, tingling, or burning.

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Multiple Sclerosis Overview

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. MS can cause varying symptoms that appear with a wide range of severity, from mild discomfort to complete disability.

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Whiplash occurs when a person's head moves backward and then forward very suddenly with great force. This injury is most common following a car collision.

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Megaloblastic Anemia

Megaloblastic anemia is a blood disorder marked by the appearance of very large red blood cells that crowd out healthy cells, causing anemia.

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Pernicious Anemia

Pernicious anemia (PA) is an autoimmune disorder in which the body fails to make enough healthy red blood cells (RBCs), resulting in vitamin B-12 deficiency. Most people experience a burning or sore tongue.

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Marine Animal Bites or Stings

This condition is considered a medical emergency. Urgent care may be required.

Stingrays have venomous spines on their tails that can cause a painful wound, nausea, and weakness, and sometimes death. Swimming or snorkeling in shallow waters puts you at risk for coming in contact.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.