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What causes back pain, muscle pain and personality change? 2 possible conditions

See a list of possible causes in order from the most common to the least.



In hyperparathyroidism, the parathyroid glands make too much of their hormone. It affects a number of body systems and can cause skin changes, including brittle nails and itching.

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Porphyrias are rare types of genetic blood disorders in which patients have a defect in heme production, an important part of hemoglobin. Blisters are a sign of porphyria cutanea tarda, the most common type of porphyria.

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