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What causes anemia and loss of appetite? 16 possible conditions

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See a list of possible causes in order from the most common to the least.



The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause complications like obesity and heart disease.

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Iron Deficiency Anemia

Iron-deficiency anemia is the most common type of anemia, which occurs when the body does not have enough of the mineral iron. The body needs iron to produce hemoglobin.

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Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an immune reaction to gluten. Symptoms vary but can include arthritis, fatigue, and abdominal symptoms.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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Thalassemia is an inherited blood disorder that results in excessive destruction of red blood cells (anemia). Symptoms depend on its severity, and can range from minor anemia to enlargement of organs or fetal death.

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Ulcerative Colitis

Ulcerative colitis is an inflammatory bowel disease. It occurs when the lining of the large intestine (colon or bowel) and the rectum become inflamed.

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Megaloblastic Anemia

Megaloblastic anemia is a blood disorder marked by the appearance of very large red blood cells that crowd out healthy cells, causing anemia.

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Pernicious Anemia

Pernicious anemia (PA) is an autoimmune disorder in which the body fails to make enough healthy red blood cells (RBCs), resulting in vitamin B-12 deficiency. Most people experience a burning or sore tongue.

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Leukemia is a cancer of the blood cells. Excessive sweating at night, fatigue, weight loss, bone pain, and easy bleeding or bruising are signs of this disease.

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E. coli Infection

E. coli is a type of bacteria normally found in intestines. But certain kinds of E. coli can cause infection and severe symptoms like diarrhea and dehydration.

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Learn about sarcoidosis and its causes, symptoms, diagnosis, treatment, and potential complications.

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Dissection of the Aorta

This condition is considered a medical emergency. Urgent care may be required.

The aorta is a large artery that carries blood out of your heart. If you experience a dissection of the aorta, it means that blood has entered the wall of the artery, between the inner and middle layers. This can happe...

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Rheumatoid Arthritis Overview

Rheumatoid arthritis (RA) is an autoimmune disease, a disease in which the immune system mistakes the body's own cells for invaders. In RA, the immune system attacks the synovia, the membranes lining the joints.

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End-Stage Kidney Disease

In end-stage kidney disease, also known as end-stage renal disease (ESRD), the kidneys are functioning below 10 percent of their normal function.

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All About Abetalipoproteinemia

Abetalipoproteinemia (ABL) is an inherited condition that prevents the body from completely absorbing certain dietary fats. Untreated, it can cause vitamin deficiencies that may have long-term effects on your health.

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Chronic Lymphocytic Leukemia

Leukemia is a type of cancer that affects the blood and blood-forming tissues. There are many types of leukemia, each affecting different kinds of blood cells. Chronic lymphocytic leukemia, or CLL, is a cancer of th...

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.