What causes anemia and general weakness? 41 possible conditions

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See a list of possible causes in order from the most common to the least.

1

Iron Deficiency Anemia

Iron-deficiency anemia is the most common type of anemia, which occurs when the body does not have enough of the mineral iron. The body needs iron to produce hemoglobin, which carries oxygen to the body's tissues...

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2

Hypothyroidism

The thyroid gland produces a hormone that controls how your cells use energy (metabolize). Hypothyroidism occurs when the body doesn't produce enough. Untreated, it can cause comlications like obesity and heart disease.

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3

Pernicious Anemia

Pernicious anemia (PA) is an autoimmune disorder in which the body fails to make enough healthy red blood cells (RBCs), resulting in vitamin B-12 deficiency. Most people experience a burning or sore tongue.

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4

Folic Acid Deficiency Anemia

Folic acid deficiency anemia is caused by having too little vitamin B9 (folate) in your blood. Folate is necessary for your body to make new red blood cells. Red blood cells are needed to carry oxygen to your organs. I...

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5

Ulcerative Colitis

In UC, the lining of the large intestine and the rectum become inflamed. This produces tiny sores or ulcers on the lining of the colon, often accompanied by diarrhea and cramping.

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6

Thalassemia

Thalassemia is an inherited blood disorder that results in excessive destruction of red blood cells (anemia). Symptoms depend on its severity, and can range from minor anemia to enlargement of organs or fetal death.

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7

Bleeding Esophageal Varices

This condition is considered a medical emergency. Urgent care may be required.

Bleeding esophageal varices occur when swollen veins in your lower esophagus rupture and bleed due to excess pressure. This condition is a medical emergency and must be dealt with promptly.

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8

Hypovolemic Shock

This condition is considered a medical emergency. Urgent care may be required.

Hypovolemic shock (hemorrhagic shock) is a life-threatening condition that results when you lose more than 20 percent of your body's blood or fluid supply, preventing the heart from pumping sufficient blood to your body.

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9

Rheumatoid Arthritis Overview

Rheumatoid arthritis (RA) is an autoimmune disease, a disease in which the immune system mistakes the body's own cells for invaders. In RA, the immune system attacks the synovia, the membranes lining the joints.

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10

Leukemia

Leukemia is a cancer of the blood cells. Excessive sweating at night, constant fatigue, weight loss, bone pain, and easy bleeding or bruising are all signs of this disease.

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11

Hemorrhoids

Hemorrhoids are swollen veins located around the anus or in the lower rectum. According to the American Society of Colon and Rectal Surgeons, millions of Americans suffer with hemorrhoids.

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12

Megaloblastic Anemia

Megaloblastic anemia is a blood disorder marked by the appearance of very large red blood cells. Anemia is a blood disorder that results in the loss of red blood cells. Red blood cells transport oxygen through the body...

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13

Sickle Cell Anemia

Sickle cell anemia is a genetic disease of the red blood cells (RBCs). Normally RBCs are shaped like a disk. This gives them the flexibility to travel through even the smallest blood vessels. However, in people wit...

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14

End-Stage Kidney Disease

A diagnosis of end-stage kidney disease means that you are in the final stage of kidney disease, and your kidneys are not functioning well enough to meet the needs of daily life. Your kidneys are responsible fo...

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15

Dissection of the Aorta

This condition is considered a medical emergency. Urgent care may be required.

The aorta is a large artery that carries blood out of your heart. If you experience a dissection of the aorta, it means that blood has entered the wall of the artery, between the inner and middle layers. This can happe...

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16

Multiple Myeloma

Multiple myeloma is a type of cancer that affects plasma cells. Plasma cells are the white blood cells that make antibodies. Multiple myeloma causes groups of abnormal plasma cells to accumulate in the bones. This ca...

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17

Sarcoidosis

Sarcoidosis is an inflammatory disease where granulomas (clumps of immune cells, usually macrophages) form in various organs. This causes organ inflammation. Doctors believe that sarcoidosis may be caused by an abnorma...

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18

Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease-also called Ebola hemorrhagic fever or Ebola fever-is a rare and often fatal illness that humans and nonhuman primates (such as monkeys and gorillas) can contract. There have been several outbreaks o...

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19

Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder. It is caused by an immune reaction to gluten. Celiac disease is also known as: sprue nontropical sprue gluten intolerance gluten-sensitive enteropathy Gluten is a protein found i...

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20

Colorectal (Colon) Cancer

Colorectal cancer is a cancer that originates in the rectum or colon. Both of these organs are located at the lower portion of your digestive system. The colon is at the end of the large intestine and the rectum is a...

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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