What causes anemia and gastrointestinal bleeding? 14 possible conditions

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See a list of possible causes in order from the most common to the least.


Bleeding Esophageal Varices

This condition is considered a medical emergency. Urgent care may be required.

Bleeding esophageal varices occur when swollen veins in your lower esophagus rupture and bleed due to excess pressure. This condition is a medical emergency and must be dealt with promptly.

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Ulcerative Colitis

In UC, the lining of the large intestine and the rectum become inflamed. This produces tiny sores or ulcers on the lining of the colon, often accompanied by diarrhea and cramping.

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Hookworm Infections

Hookworms are parasites that affect the small intestine and lungs. The first sign of infection is usually a rash where the parasite entered the skin, followed by diarrhea.

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Amebiasis is a parasitic infection, common in tropical countries and caused by contaminated water. Symptoms can be severe and usually start one to four weeks after exposure.

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Colorectal (Colon) Cancer

Colorectal cancer is a cancer that originates in the rectum or colon. Both of these organs are located at the lower portion of your digestive system. The colon is at the end of the large intestine and the rectum is a...

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Celiac Disease (Gluten Intolerance)

Celiac disease is a digestive disorder caused by an immune reaction to gluten. Symptoms vary but can include arthritis, fatigue, and abdominal symptoms.

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Hemorrhoids, also called piles, are swollen veins located around the anus or in the lower rectum. Internal hemorrhoids develop within the anus; external hemorrhoids develop outside of the anus. Of the two forms...

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Malaria is a life-threatening disease. It is typically transmitted through the bite of a mosquito infected with Anopheles. Nausea, chills, fever, and diarrhea are common symptoms.

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Hemophilia A

Hemophilia A (factor VIII deficiency) is the most common form of the blood clotting disorder hemophilia. It can cause prolonged bleeding, tight joints, and unexplained bruising.

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Ebola Virus and Disease

This condition is considered a medical emergency. Urgent care may be required.

Ebola disease is a rare, often fatal illness. One of its late-stage symptoms is a bleeding rash over the entire body.

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Glomerulonephritis occurs when blood filtering vessels in the kidneys are damaged. This may contribute to kidney failure, which causes fatigue, insomnia, itchy skin, and other symptoms.

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Polymyalgia Rheumatica

Polymyalgia rheumatica is an inflammatory disorder that causes pain and stiffness in various parts of the body, including the shoulders, neck, arms, thighs, and hips. The cause of this disorder is unknown.

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E. coli Infection

E. coli is a type of bacteria normally found in intestines. But certain kinds of E. coli can cause infection and severe symptoms like diarrhea and dehydration.

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Christmas Disease (Hemophilia B)

Also called hemophilia B or factor IX hemophilia, Christmas disease is a rare genetic disorder in which your blood does not clot properly. A common symptom is unexplained or excessive bruising.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.
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