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What causes abnormal urine color and tired? 14 possible conditions

See a list of possible causes in order from the most common to the least.



Hepatitis refers to an inflammatory condition of the liver. It's commonly caused by a viral infection, but there are other possible causes of hepatitis.

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Pyelonephritis is an inflammation of the kidney and upper urinary tract. Symptoms include flushed skin, back pain, fever, and nausea.

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Idiopathic Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) is a group of blood disorders that occur when red blood cells are destroyed faster than they're produced. Symptoms include weakness, shortness of breath, rapid heart rate, and others.

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Bladder Cancer

Bladder cancer occurs in the tissues of the bladder, which is the organ that holds urine. Fatigue, weight loss, painful or frequent urination, and abdominal or back pain are symptoms.

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Glomerulonephritis is a serious illness that can be life-threatening and requires immediate treatment. The condition is sometimes called nephritis.

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Drug-Induced Immune Hemolytic Anemia

Drug-induced immune hemolytic anemia (DIIHA) is a rare blood disorder in which your immune system begins attacking your red blood cells. Symptoms include dark urine, fast heartbeat, and jaundice.

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Tuberculosis (TB) is a highly infectious disease that primarily affects the lungs. A severe and long-lasting cough, fever, and night sweats could indicate an active TB infection.

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Endocarditis is inflammation of the inner lining of the heart. Possible symptoms of this condition include pale skin, chills, and night sweats.

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Bladder Infection

A bladder infection is a bacterial infection. It also may be called a urinary tract infection (UTI), which refers to infection anywhere in the urinary tract, including the bladder, kidneys, ureters, or urethra.

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Hepatitis A

Hepatitis A (HAV) is a short-term type of hepatitis. It usually requires no treatment, but symptoms include fever, nausea, jaundice, and itchy skin, among others.

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Hepatitis B

Hepatitis B is liver inflammation caused by the hepatitis B virus (HBV). It can be chronic or acute, but most cases are chronic. This disease is easily spread through blood, saliva, and other body fluids.

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Infective Endocarditis

Infective endocarditis is an infection of the heart, normally caused by bacteria in the blood stream. It is a serious medical condition. If left untreated, the infection can damage your heart and may even cause death.

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Hepatitis D

Hepatitis D is an infection of the hepatitis D virus that causes your liver to swell and is uncommon in the United States. It is almost always contracted by people with hepatitis B.

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Hepatitis C

Hepatitis C is a disease that causes inflammation and infection in the liver. Symptoms of chronic cases may not be obvious at first, whereas acute hepatitis C sets in quickly after exposure to the virus.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.