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What causes abdominal pain and tired? 57 possible conditions

See a list of possible causes in order from the most common to the least.


PMS (Premenstrual Syndrome)

PMS symptoms start five to 11 days before menstruation and typically go away once menstruation begins. The cause of PMS is unknown.

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Endometriosis occurs when tissue from the lining of the uterus grows outside of it, forming growths on the ovaries and in the pelvic region.

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Lactose Intolerance

Lactose intolerence occurs when a person's small intestine can't break down lactose, an enzyme found in dairy foods. The condition can cause many gastrointestinal symptoms.

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Peptic Ulcer

Peptic ulcers are sores that develop in the lining of the stomach, esophagus, or rarely in small intestine. They are usually caused by H. pylori, excessive NSAID or alcohol usage, smoking, or stomach cancer.

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Hepatitis is swelling and inflammation of the liver. It's usually caused by a viral infection. There are several types of hepatitis, including: A, B, C, D, and E. Symptoms may not occur until liver damage occurs.

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Infectious Mononucleosis

Infectious mononucleosis, or "mono," is a group of symptoms caused by the Epstein-Barr virus. One potential symptom is a pink rash that looks like the measles.

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Bleeding or spotting, increased need to urinate, tender breasts, fatigue, nausea, and missed period are signs of pregnancy.

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Leukemia is a cancer of the blood cells. Excessive sweating at night, constant fatigue, weight loss, bone pain, and easy bleeding or bruising are all signs of this disease.

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Stomach Ulcer

Stomach ulcers are painful sores in the stomach lining or small intestine. They occur when the mucus that protects the stomach from digestive juices is reduced.

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H. Pylori Infection

H. pylori are a type of bacteria that may not cause problems. However, sometimes it can cause pain, bloating, and burping, and may lead to ulcers or stomach cancer.

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Underactive Pituitary Gland (Hypopituitarism)

The pituitary gland releases hormones that play roles in body processes like bone growth and metabolism. An underactive pituitary can disrupt these processes. Causes may include tumors, traumatic injuries, and diseases.

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Addison’s Disease

Addison's disease occurs when the adrenal cortex is damaged and the adrenal glands don't produce enough of the steroid hormones cortisol and aldosterone.

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Crohn’s Disease

Crohn's disease is a chronic bowel disease that causes severe inflammation of the digestive tract. It is associated with abdominal pain, diarrhea, and may affect your quality of life. Crohn's disease is characterized b...

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Colitis is inflammation of the colon, often causing discomfort and pain in the abdomen, as well as other gastrointestinal symptoms. Colitis has many possible causes, which determine the type.

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Ulcerative Colitis

In UC, the lining of the large intestine and the rectum become inflamed. This produces tiny sores or ulcers on the lining of the colon, often accompanied by diarrhea and cramping.

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Diabetes Overview

Diabetes is a group of chronic metabolic diseases caused by defects in insulin production or function. Advanced diabetes may cause stomach pain, nausea, dizziness, and cramps.

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Pelvic Inflammatory Disease (PID)

Pelvic inflammatory disease (PID) is an infection of the reproductive organs in women caused by bacteria. It's marked by pain in the abdomen, especially during urination or sex.

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Sickle Cell Anemia

Sickle cell anemia is a genetic disease that causes red blood cells to have an abnormal shape, causing blood flow problems. This can lead to tissue damage and pain, as well as enlarged spleen, anemia, and other symptoms.

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Colorectal (Colon) Cancer

Colorectal cancer is a cancer that originates in the rectum or colon. Both of these organs are located at the lower portion of your digestive system. The colon is at the end of the large intestine and the rectum is a...

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Pyelonephritis is an inflammation of the kidney and upper urinary tract. Symptoms include flushed skin, back pain, fever, and nausea.

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This feature is for informational purposes only and should not be used to diagnose.
Please consult a healthcare professional if you have health concerns.